Pulmonary defense against environmental injury depends on airway mucus, which traps
inhaled toxins that are then cleared from the lungs by ciliary beating and cough. This review …

Mucous hypersecretion is a major cause of airway obstruction in asthma, chronic obstructive
pulmonary disease, and cystic fibrosis. EGFR ligands and IL-13 are known to stimulate …

Respiratory tract secretions consist of mucus, surfactant, and periciliary fluid. The airway
surface fluid is present as a bilayer, with a superficial gel or mucous layer and a layer of …

Airway mucus is a complex airway secretion whose primary function as part of the
mucociliary transport mechanism is to to serve as renewable and transportable barrier …

The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Airway mucus obstruction is a hallmark of many chronic lung diseases including rare genetic
disorders such as cystic fibrosis (CF) and primary ciliary dyskinesia, as well as common lung …

Respiratory mucous glycoproteins may serve a number of protective functions for the
airways; however, excessive secretions contribute to the morbidity of a variety of diseases …

Clinicians and their patients are troubled by respiratory secretions, and standard practice
calls for efforts to clear secretions from the lungs. On one hand, mucus production and …

Mucus secretion is the first-line defense against the barrage of irritants that inhalation of
approximately 500 L of air an hour brings into the lungs. The inhaled soot, dust, microbes …

The mucus lining of the respiratory tract originates from products of secretory cells
interspersed among mucosal cells or within submucosal glands and protects the underlying …