Proinflammatory cytokines are involved in clearance of Plasmodium falciparum, and very
high levels of these cytokines have been implicated in the pathogenesis of severe malaria …

Inflammatory cytokines play an important role in human immune responses to malarial
disease. However, the role of these mediators in disease pathogenesis, and the relationship …

The balance between pro-and antiinflammatory cytokines may be important in malaria
presentation and outcome. Malaria tends to be more severe in children than in adults …

Animal models suggest that cytokines and chemokines play a role in cerebral malaria (CM)
pathogenesis, but levels of a number of cytokines and chemokines thought to be important …

Cell‐mediated immunity and cytokines are probably involved in the pathogenesis of malaria.
To investigate the role and the activity of different immune cells, we measured levels of …

Background The factors involved in the progression from Plasmodium falciparum infection to
severe malaria (SM) are still incompletely understood. Altered antibody and cellular …

Background Young children are at greatest risk for malaria-associated morbidity and
mortality. The immune response of young children differs in fundamental ways from that of …

Severe Plasmodium falciparum malaria anemia (SMA) is a major cause of mortality in
pediatric wards. Variations in inflammatory mediator production play an essential role in …

Background Severe malaria (SM) is a fatal multi-system disease which accounted for an
estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are …

Anemia is an important complication of malaria, and its pathogenesis is not well understood.
To gain insight into potential age-related relationships between tumor necrosis factor alpha …