No survival benefit with early incorporation of thoracic radiotherapy using daily fractionation in patients with limited-stage small cell lung cancer undergoing …

BH Kim, C Song, HJ Kim - Radiotherapy and Oncology, 2023 - Elsevier
Background When concurrent chemoradiotherapy (CCRT) is administered for limited-stage
small cell lung cancer (LS-SCLC), the early incorporation of thoracic radiotherapy (TRT) is …

[HTML][HTML] Is there a place for optimizing thoracic radiotherapy in limited-stage small cell lung cancer after twenty years?

JM Barros, MM Rizzo, JO Chiozza… - World Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Thoracic radiotherapy (TRT) is one of the main treatments in limited-stage small cell lung
cancer (LS-SCLC). Hyperfractionated TRT (45 Gy, 1.5 Gy twice daily) has been the standard …

Timing of thoracic radiation therapy with chemotherapy in limited-stage small-cell lung cancer: survey of US radiation oncologists on current practice patterns

MJ Farrell, JB Yahya, C Degnin, Y Chen, JM Holland… - Clinical Lung Cancer, 2018 - Elsevier
Introduction For limited-stage small-cell lung cancer (LS-SCLC), National Comprehensive
Cancer Network guidelines recommend that thoracic radiotherapy (TRT) be delivered …

Effects of thoracic radiotherapy timing and duration on progression‐free survival in limited‐stage small cell lung cancer

S Zhao, T Zhou, S Ma, Y Zhao, J Zhan, W Fang… - Cancer …, 2018 - Wiley Online Library
Concurrent chemoradiotherapy (CRT) has been recommended and applied widely as the
standard treatment for limited‐stage small cell lung cancer (LS‐SCLC). However …

Treatment time to the end of thoracic radiotherapy has more predictive power for survival than radiation dose intensity in patients with limited-stage small-cell lung …

JU Jeong, W Jeon, SJ Ahn, YC Kim… - Oncology …, 2020 - spandidos-publications.com
The optimal protocol for thoracic radiotherapy (TRT) in combination with chemotherapy in
patients with limited-stage small-cell lung cancer (LS-SCLC) remains elusive. The present …

Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: a London Lung Cancer Group multicenter …

SG Spiro, LE James, RM Rudd, CW Trask… - Journal of clinical …, 2006 - ascopubs.org
Purpose To replicate an earlier National Cancer Institute of Canada (NCIC) trial that
examined the effect on survival of the timing of thoracic radiotherapy (TRT) in patients with …

[HTML][HTML] Impact of thoracic radiotherapy timing in limited-stage small-cell lung cancer: usefulness of the individual patient data meta-analysis

D De Ruysscher, B Lueza, C Le Péchoux… - Annals of …, 2016 - Elsevier
Background Chemotherapy (CT) combined with radiotherapy is the standard treatment of
'limited-stage'small-cell lung cancer. However, controversy persists over the optimal timing …

Final survival data from a randomized phase II trial comparing high-dose with standard-dose twice-daily (BID) thoracic radiotherapy (TRT) in limited stage small-cell …

BHH Gronberg, KT Killingberg, Ø Fløtten, MM Bjaanæs… - 2023 - ascopubs.org
8512 Background: Concurrent chemotherapy and TRT is standard treatment of LS SCLC.
BID TRT of 45 Gy/30 fractions is the most recommended schedule. Trials report 5-year …

Phase III trial of concurrent thoracic radiotherapy (TRT) with either the first cycle or the third cycle of cisplatin and etoposide chemotherapy to determine the optimal …

K Park, JM Sun, SW Kim, M Ahn, JS Ahn, DH Lee… - 2012 - ascopubs.org
7004 Background: Concurrent thoracic radiotherapy (TRT) with chemotherapy has been
regarded as optimal treatment for limited-disease small cell lung cancer (SCLC). However …

Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer

DB Fried, DE Morris, C Poole, JG Rosenman… - Journal of clinical …, 2004 - ascopubs.org
Purpose We employed meta-analytic techniques to evaluate early (E) versus late (L) timing
of thoracic radiation therapy (RT) in limited-stage small-cell lung cancer (LS-SCLC). In …