Management of severe complications in Behçet's disease with TNF inhibitors

AC Desbois, H Vallet, F Domont… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: The efficacy of anti-TNFα agents has been recently evaluated in many studies
in Behçet's disease (BD), particularly in ocular and life-threatening manifestations such as …

Anti-tumour necrosis factor-alpha agent therapy, compared with conventional therapy, reduces the relapse of uveitis in patients with behçet's disease: A systematic …

X Zhou, X Shi, Y Ren, T Yan, Q Ye - Frontiers in Pharmacology, 2022 - frontiersin.org
Purpose: Anti-tumour necrosis factor-alpha (TNF-α) agents are often used for Behçet's
disease (BD) in clinical practice, but they have not been validated by a high level of …

Anti-TNF-α therapy in patients with refractory uveitis due to Behçet's disease: a 1-year follow-up study of 124 patients

V Calvo-Río, R Blanco, E Beltrán… - …, 2014 - academic.oup.com
Objective. The aim of this study was to assess the efficacy of anti-TNF-α therapy in refractory
uveitis due to Behçet's disease (BD). Methods. We performed a multicentre study of 124 …

Biological therapies for the treatment of Behçet's disease-related uveitis beyond TNF-alpha blockade: a narrative review

J Sota, D Rigante, G Lopalco, B Frediani… - Rheumatology …, 2018 - Springer
Intraocular inflammation is one of the more relevant complications of Behçet's disease (BD),
which tends to respond poorly to different medications. The ocular histopathologic changes …

Comparing biologic options for the management of Behcet's disease-related uveitis

A Vitale, V Caggiano, V Berlengiero… - Expert Review of …, 2023 - Taylor & Francis
Introduction Behçet's disease (BD) associated uveitis occurs in approximately 50–70% of
the patients. Ocular involvement in BD may induce a severe affection of visual function …

[PDF][PDF] IL-6 blockade for Behçet's disease: review on 31 anti-TNF naive and 45 anti-TNF experienced patients

A Arida, D Saadoun, PP Sfikakis - Clin Exp Rheumatol, 2022 - clinexprheumatol.org
Objective. Despite the remarkable efficacy of anti-TNF agents in Behçet's disease (BD),
unmet therapeutic needs for refractory or intolerant patients to these drugs still exist. Based …

Anti-TNF therapy in the management of Behçet's disease—review and basis for recommendations

PP Sfikakis, N Markomichelakis, E Alpsoy… - …, 2007 - academic.oup.com
Behcet's disease (BD) is a multisystem, chronic-relapsing, inflammatory disorder classified
among the vasculitides [1, 2]. It has a worldwide distribution being more prevalent in the …

Predictors of sustained clinical response in patients with Behçet's disease-related uveitis treated with infliximab and adalimumab

C Fabiani, A Vitale, D Rigante, G Emmi, G Lopalco… - Clinical …, 2018 - Springer
To identify clinical variables capable of predicting long-term treatment duration of TNF-α
inhibition in patients with Behçet's disease (BD)-related uveitis. Demographic, clinical, and …

[PDF][PDF] Induction of ocular Behçet's disease remission after short-term treatment with infliximab: A case series of 11 patients with a follow-up from 4 to 16 years

PP Sfikakis, A Arida, DS Ladas… - Clin Exp …, 2019 - clinexprheumatol.org
Objective. Initial recommendations on anti-TNF treatment for Behçet's disease (BD) included
an intravenous infliximab infusion for acute posterior uveitis to achieve a fast-onset …

Evaluation of the long-term efficacy and safety of infliximab treatment for uveitis in Behçet's disease: a multicenter study

M Takeuchi, T Kezuka, S Sugita, H Keino, K Namba… - Ophthalmology, 2014 - Elsevier
Purpose To evaluate the long-term efficacy and safety of infliximab for the treatment of
uveitis in Behçet's disease (BD). Design Retrospective multicenter study using a …