Abstract Background Lysophosphatidic acids (LPAs) belong to a class of bioactive
lysophospholipids with multiple functions including immunomodulatory roles in tumor …

LPAR6 is the most recently determined G-protein-coupled receptor of the lysophosphatidic
acid receptor, and very few of studies have demonstrated the performance of LPAR6 in …

Purpose Lysophosphatidic acid (LPA) exerts various physiological and pathological effects
by activating its distinct G-protein-coupled LPA receptors. We demonstrated that LPA can …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer worldwide. Despite improvement in therapeutic strategies, the prognosis of …

Lysophosphatidic acid (LPA) is a bioactive lipid that interacts with G protein-coupled LPA
receptors (LPA receptor-1 (LPA1) to LPA6). Here, we investigated the effects of LPA …

OBJECTIVE: This study aims to explore the diagnostic and prognostic values of
Lysophosphatidic acid receptor 5 (LPAR5) in non-small-cell lung cancer (NSCLC) and its …

Lysophosphatidic acid (LPA), as a bioactive lipid, plays a variety of physiological and
pathological roles via activating six types of G-protein-coupled LPA receptors (LPA1–6). Our …

Lysophosphatidic acid (LPA) is a bioactive lipid which increases in concentration locally and
systemically across different cancer types. Yet, the exact mechanism (s) of how LPA affects …

Purpose Lysophosphatidic acid (LPA) is a multifunctional lipid mediator involved in
triggering tumor cell invasion and metastasis, as well as malignant cell growth. LPA is also …

Background Lysophosphatidic acid receptor 3 (LPAR3) is coupled to G α i/o and G α 11/q
signaling. Previously, we reported that LPAR3 is highly methylated in carcinogen-induced …