Preventing human-to-mosquito transmission of malaria parasites provides possible
solutions to interrupt the malaria parasite life cycle for malaria elimination. The development …

The ability to target human–mosquito parasite transmission challenges global malaria
elimination. However, it is not obvious what a transmission-blocking drug will look like; …

Objectives The development of drugs to reduce malaria transmission is an important part of
malaria eradication plans. We set out to develop and validate a combination of new …

Drugs that kill or inhibit the sexual stages of Plasmodium could potentially amplify or
synergize the impact of other interventions by blocking transmission to mosquitoes …

Background Despite recent successes at controlling malaria, progress has stalled with an
estimated 219 million cases and 435,000 deaths in 2017 alone. Combined with emerging …

Plasmodium parasites have a complex life cycle that includes development in the human
host as well as the Anopheles vector. Successful transmission of the parasite between its …

Malaria remains one of the most prevalent tropical and infectious diseases in the world, with
an estimated more than 200 million clinical cases every year. In recent years, the mosquito …

Preventing transmission is an important element of malaria control. However, most of the
current available methods to assay for malaria transmission blocking are relatively low …

A major goal of the worldwide malaria eradication program is the reduction and eventual
elimination of malaria transmission. All currently available antimalarial compounds were …

Malaria is a disease with a devastating impact affecting 216 million people each year and
causing 655,000 deaths, most of which are children under 5 years old. Recent appreciation …