Abstract Background The Th1 cell-specific transcription factor TBX21 functions as a
regulator of expression of a Th1 cytokine, interferon gamma (IFN-γ). However, the specific …

Abstract T-box 3 (Tbx3), a member of the T-box transcription factor family, serves a crucial
role in embryonic development and cancer progression. Previous studies have …

Purpose Long non-coding RNAs (lncRNAs) have been reported to play important roles in
tumor biology. In this study, we aimed to investigate the effects of T-box transcription factor 5 …

Abstract Background Enhancer RNAs (eRNAs) are demonstrated to be closely associated
with tumourigenesis and cancer progression. However, the role of eRNAs in lung …

T-box transcription factor 5 (TBX5), a member of the conserved T-box transcription factor
family that functions in organogenesis and embryogenesis, has recently been identified as a …

Abstract The TBX2 subfamily (TBXs 2, 3, 4 and 5) transactivates or represses genes
involved in lung organogenesis. Yet TBX2 subfamily expression in pathogenesis of non …

Abstract T-box2 (TBX2) expression has been reported to be related to aggressive tumor
features. However, the role of TBX2 in non-small-cell lung cancer (NSCLC) tumorigenesis …

The T-box factors belong to an ancient protein family, which comprises a cluster of
evolutionarily-conserved transcription factors that regulate gene expression and that are …

T-box transcription factor 15 (TBX15) is upregulated in a variety of tumors and has been
reported to promote uncontrolled proliferation of tumor cells and induce tumor cells to avoid …

T-box (TBX) transcription factors are evolutionary conserved genes and master
transcriptional regulators. In mammals, TBX2 subfamily (TBX2, TBX3, TBX4, and TBX5) …