[HTML][HTML] Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study

AM Hughes, E Sanderson, T Morris, Z Ayorech, M Tesli… - elife, 2022 - elifesciences.org
Background: Higher BMI in childhood is associated with emotional and behavioural
problems, but these associations may not be causal. Results of previous genetic studies …

Body mass index and depressive symptoms: Instrumental‐variables regression with genetic risk score

M Jokela, M Elovainio… - Genes, Brain and …, 2012 - Wiley Online Library
The causal role of obesity in the development of depression remains uncertain. We applied
instrumental‐variables regression (Mendelian randomization) to examine the association of …

Developmental trajectory of body weight in youths at risk for major mood disorders

N Adepalli, J Cumby, N Campbell, B Pavlova… - JAMA Network …, 2023 - jamanetwork.com
Importance Mood disorders are associated with increased body weight, especially in
females, but it remains unknown when the weight increase starts. Objectives To examine …

Revisiting Mendelian randomization studies of the effect of body mass index on depression

S Walter, LD Kubzansky, KC Koenen… - American Journal of …, 2015 - Wiley Online Library
Mendelian Randomization studies, which use genetic instrumental variables (IVs) as quasi‐
experiments to estimate causal effects, report inconsistent findings regarding effects of body …

Mendelian randomization analysis identified causal Association of Childhood Obesity with adult major depressive disorder

SS Yan, Q Xu, BX Han, JJ Ni, XT Wei, GJ Feng… - Pediatric …, 2022 - Wiley Online Library
Background Childhood obesity is associated with adult major depressive disorder (MDD),
but their causality is not clear. Methods We performed a two‐sample Mendelian …

The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI

EK Do, BC Haberstick, RB Williams… - International Journal of …, 2019 - nature.com
Abstract Background/Objectives Although childhood attention deficit hyperactivity disorder
(ADHD) has been previously associated with concurrent and later obesity in adulthood, the …

The association between childhood depression and adulthood body mass index

DS Pine, RB Goldstein, S Wolk, MM Weissman - Pediatrics, 2001 - publications.aap.org
Objective. Stress in childhood relates to both childhood depression and elevated adult body
mass index (BMI), a measure of relative overweight. However, there are limited data on the …

Are there causal relationships between attention-deficit/hyperactivity disorder and body mass index? Evidence from multiple genetically informed designs

CY Liu, T Schoeler, NM Davies, H Peyre… - International Journal …, 2021 - academic.oup.com
Background Attention-deficit/hyperactivity disorder (ADHD) and body mass index (BMI) are
associated. However, it remains unclear whether this association reflects causal …

Maternal prepregnancy body mass index and offspring attention‐deficit/hyperactivity disorder: a quasi‐experimental sibling‐comparison, population‐based design

ED Musser, MT Willoughby, S Wright… - Journal of Child …, 2017 - Wiley Online Library
Background High maternal prepregnancy body mass index (BMI) has been associated with
increased risk of offspring attention‐deficit/hyperactivity disorder (ADHD). However, whether …

Associations between depression and obesity in parents and their late-adolescent offspring: a community-based study

NR Marmorstein, WG Iacono - Psychosomatic medicine, 2016 - journals.lww.com
Objective Major depressive disorder (MDD) and obesity are associated within individuals,
but little is known about the association between MDD and obesity within families. We …