Food intake is tightly regulated by complex and coordinated gut-brain interactions. Nutrients
rapidly modulate activity in key populations of hypothalamic neurons that regulate food …

The brain regulates food intake by processing sensory cues and peripheral physiological
signals, but the neural basis of this integration remains unclear. Hypothalamic, agouti …

To maintain energy homeostasis, orexigenic (appetite-inducing) and anorexigenic (appetite
suppressing) brain systems functionally interact to regulate food intake. Within the …

Feeding behavior is exquisitely regulated by homeostatic and hedonic neural substrates that
integrate energy demand as well as the reinforcing and rewarding aspects of food …

Body weight is regulated by interoceptive neural circuits that track energy need, but how the
activity of these circuits is altered in obesity remains poorly understood. Here we describe …

Hypothalamic feeding circuits have been identified as having innate synaptic plasticity,
mediating adaption to the changing metabolic milieu by controlling responses to feeding …

Communication between the gut and brain is critical for homeostasis, but how this
communication is represented in the dynamics of feeding circuits is unknown. Here we …

Multiple hypothalamic neuronal populations that regulate energy balance have been
identified. Although hypothalamic glia exist in abundance and form intimate structural …

While energy balance is critical to survival, many factors influence food intake beyond
caloric need or" hunger." Despite this, some neurons that drive feeding in mice are routinely …

It is well recognized that feeding behavior in mammals is orchestrated by neurons within the
medial basal hypothalamus. However, it remains unclear whether food intake is also under …