[HTML][HTML] Targeting transcription factors for therapeutic benefit in rheumatoid arthritis
T Balendran, K Lim, JA Hamilton… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a destructive inflammatory autoimmune disease that causes
pain and disability. Many of the currently available drugs for treating RA patients are aimed …
pain and disability. Many of the currently available drugs for treating RA patients are aimed …
Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy
SW Tas, PHJ Remans, KA Reedquist… - Current pharmaceutical …, 2005 - ingentaconnect.com
Many chronic inflammatory diseases are associated with deregulated intracellular signal
transduction pathways. Resultant pathogenic interactions between immune and stromal …
transduction pathways. Resultant pathogenic interactions between immune and stromal …
Molecular targets of rheumatoid arthritis
H Okamoto, D Hoshi, A Kiire… - … & Allergy-Drug …, 2008 - ingentaconnect.com
Rheumatoid arthritis (RA) is a multifactorial disease characterized by chronic inflammation of
the joints. Both genetic and environmental factors are involved in the pathogenesis of joint …
the joints. Both genetic and environmental factors are involved in the pathogenesis of joint …
Targeting pathways and integrated approaches to treat rheumatoid arthritis
SD Dwivedi, K Yadav, A Bhoi, KK Sahu… - Critical Reviews™ in …, 2024 - dl.begellhouse.com
Rheumatoid arthritis (RA) is a chronic symmetrical systemic disorder that not only affects
joints but also other organs such as heart, lungs, kidney, and liver. Approximately there is …
joints but also other organs such as heart, lungs, kidney, and liver. Approximately there is …
[HTML][HTML] Targeting toll-like receptor (TLR) pathways in inflammatory arthritis: two better than one?
S Santos-Sierra - Biomolecules, 2021 - mdpi.com
Inflammatory arthritis is a cluster of diseases caused by unregulated activity of the immune
system. The lost homeostasis is followed by the immune attack of one's self, what damages …
system. The lost homeostasis is followed by the immune attack of one's self, what damages …
[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy
Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …
progression leads to joint deformity and associated loss of function, which significantly …
Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis
S Liu, H Ma, H Zhang, C Deng, P Xin - Clinical Immunology, 2021 - Elsevier
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …
Rheumatoid arthritis: biological therapy other than anti-TNF
D Rossi, V Modena, S Sciascia, D Roccatello - International …, 2015 - Elsevier
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases and is
characterized by synovitis that causes joint damage. The introduction of biologic agents has …
characterized by synovitis that causes joint damage. The introduction of biologic agents has …
[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …
Novel immunotherapeutic avenues for rheumatoid arthritis
L Semerano, E Minichiello, N Bessis… - Trends in Molecular …, 2016 - cell.com
Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease. It leads to
irreversible joint damage, physical handicap, and reduced life expectancy. The past two …
irreversible joint damage, physical handicap, and reduced life expectancy. The past two …
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