Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials

B Mangla, S Javed, MH Sultan, P Kumar… - Phytotherapy …, 2021 - Wiley Online Library
Traditionally, herbal supplements have shown an exceptional potential of desirability for the
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …

[HTML][HTML] Sulforaphane's multifaceted potential: From neuroprotection to anticancer action

RA Otoo, AR Allen - Molecules, 2023 - mdpi.com
Sulforaphane (SFN) is a naturally occurring compound found in cruciferous vegetables such
as broccoli and cauliflower. It has been widely studied for its potential as a neuroprotective …

[PDF][PDF] Current potential health benefits of sulforaphane

JK Kim, SU Park - 2016 - 129.217.131.68
Sulforaphane [SFN: 1-isothiocyanato-4-(methylsulfinyl) butane] belongs to the
isothiocyanate class of phytochemicals. Glucoraphanin, a glucosinolate precursor of SFN, is …

Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency

JW Fahey, KL Wade, SL Wehage… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope The isothiocyanate sulforaphane (SF) from broccoli is one of the most potent known
inducers of the cytoprotective phase 2 response. Its role in a host of biochemical pathways …

Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review

S Khan, KA Awan, MJ Iqbal - Journal of Food biochemistry, 2022 - Wiley Online Library
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various
biological benefits for health promotion and disease prevention. This compound is …

Sulforaphane as an anticancer molecule: Mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems

MM Kamal, S Akter, CN Lin, S Nazzal - Archives of pharmacal research, 2020 - Springer
Sulforaphane is an isothiocyanate compound that has been derived from cruciferous
vegetables. It was shown in numerous studies to be active against multiple cancer types …

New highlights on the health-improving effects of sulforaphane

A Briones-Herrera, D Eugenio-Pérez… - Food & function, 2018 - pubs.rsc.org
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN),
which is the most studied member of isothiocyanates, on both in vivo and in vitro models of …

Sulforaphane: its “coming of age” as a clinically relevant nutraceutical in the prevention and treatment of chronic disease

CA Houghton - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
A growing awareness of the mechanisms by which phytochemicals can influence upstream
endogenous cellular defence processes has led to intensified research into their potential …

Natural sulforaphane as a functional chemopreventive agent: including a review of isolation, purification and analysis methods

H Liang, Q Yuan - Critical reviews in biotechnology, 2012 - Taylor & Francis
Epidemiological data show that a diet rich in fruits and vegetables can reduce the risk from a
number of cancers and chronic diseases. Sulforaphane (SF), a phytochemical constituent of …

[PDF][PDF] Potential health benefits of sulforaphane: a review of the experimental, clinical and epidemiological evidences and underlying mechanisms

F Elbarbry, N Elrody - J Med Plants Res, 2011 - academicjournals.org
Extensive epidemiological evidence and animal experimental studies suggest that
cruciferous vegetables may prevent or delay various inflammatory disorders, including …