Purpose Exosomes are small nanoscale vesicles secreted from cells. Exosome-based
therapeutic approaches have been evaluated in treating ischemic diseases. In the present …

Type 1 diabetes, has been recognized as an autoimmune disease. Like other
immunological conditions, regulation of immune response is a key strategy to control the …

Nonhealing wounds in diabetes remain a global clinical and research challenge. Exosomes
are primary mediators of cell paracrine action, which are shown to promote tissue repair and …

Exosomes are extracellular vesicles (EVs) secreted from a majority of cell types. Exosomes
play a role in healthy and pathogenic intercellular interactions via the transfer of proteins …

Diabetes mellitus (DM) is among the chronic metabolic disorders that its incidence rate has
shown an increase in developed and wealthy countries due to lifestyle and obesity. The …

Ischaemic disorders are leading causes of morbidity and mortality worldwide. While the
current therapeutic approaches have improved life expectancy and quality of life, they are …

Diabetes mellitus, the ninth leading cause of death worldwide, is a type of metabolic disease
characterized by hyperglycemia. Without timely and effective treatment, many ensuing …

Exosomes are vesicles with a particle size of 30‑120 nm that are secreted by cells through
exocytosis. The composition of an exosome includes a lipid bilayer and its internal package …

Diabetic vascular complications (DVC) including macrovascular and microvascular lesions,
have a significant impact on public health, and lead to increased patient mortality …

Chronic, subclinical inflammation was often observed in the diabetic wound area, causing
inadequate and delayed wound-healing effects by failing to initiate cell migration …