Increasing concern about the risks and limited evidence supporting the therapeutic benefit of
long-term opioid therapy for chronic noncancer pain are leading prescribers to consider …

Objectives This paper describes characteristics of opioid use episodes for noncancer pain
and defines thresholds for de facto long-term opioid therapy. Methods CONSORT …

Background: Opioids have been utilized for thousands of years to treat pain and their use
continues to escalate. It is estimated that 90% of the patients who present to pain centers …

Objective To study differences in treatment outcomes between patients with chronic
noncancer pain taking vs those not taking maintenance opioids at admission to a pain …

Background: Opioid abuse has increased at an alarming rate. However, available evidence
suggests a wide variance in the use of opioids, as documented by different medical …

Objective. There is inadequate evidence of long-term benefit and growing evidence of the
risks of chronic opioid therapy (COT). Opioid dose reduction, or opioid tapering, may reduce …

Background: Long-term opioid use for chronic non-cancer pain has increased substantially
in recent years despite the paucity of strong supporting scientific data and concerns …

Prescription opioid use continues to contribute to significantmorbidityandmortalityintheUnited…
. 1-4 In 2017, 17029ofthe47600opioid-relatedoverdosedeaths involved prescription opioids …

Safe and effective chronic opioid therapy (COT) for chronic noncancer pain requires clinical
skills and knowledge in both the principles of opioid prescribing and in the assessment and …

Use of chronic opioid therapy for chronic noncancer pain has increased substantially. The
American Pain Society and the American Academy of Pain Medicine commissioned a …