[HTML][HTML] ADSC-Exos enhance functional recovery after spinal cord injury by inhibiting ferroptosis and promoting the survival and function of endothelial cells through …
S Wu, Z Chen, Y Wu, Q Shi, E Yang, B Zhang… - Biomedicine & …, 2024 - Elsevier
Background Spinal cord injury (SCI) is a devastating disease that causes major motor,
sensory and autonomic dysfunctions. Currently, there is a lack of effective treatment. In this …
sensory and autonomic dysfunctions. Currently, there is a lack of effective treatment. In this …
Adipose-derived mesenchymal stem cell exosomes ameliorate spinal cord injury in rats by activating the Nrf2/HO-1 pathway and regulating microglial polarization
Y Luo, Y He, Y Wang, Y Xu, L Yang - Folia Neuropathologica, 2023 - termedia.pl
As of now, there are no satisfactory treatments for spinal cord injury (SCI), so new
therapeutic approaches are necessary to be explored. Adipose-derived mesenchymal stem …
therapeutic approaches are necessary to be explored. Adipose-derived mesenchymal stem …
Exosomes from Long Noncoding RNA-Gm37494-ADSCs Repair Spinal Cord Injury via Shifting Microglial M1/M2 Polarization
M Shao, M Jin, S Xu, C Zheng, W Zhu, X Ma, F Lv - Inflammation, 2020 - Springer
Spinal cord injury (SCI) may lead to severe motor and sensory dysfunction, causing high
mortality and disability rates. Adipose tissue-derived mesenchymal stem/stromal cells …
mortality and disability rates. Adipose tissue-derived mesenchymal stem/stromal cells …
Effects of ADSC-Derived Exosome LRRC75A-AS1 on Anti-inflammatory Function After SCI
X Xing, P Xu, X Xing, Z Xu, Z Huang, Z Li, X Li… - Applied Biochemistry …, 2024 - Springer
Spinal cord injury (SCI) is a highly debilitating disorder of the central nervous system that
can severely impact an affected patient's quality of life. This study aimed to examine how …
can severely impact an affected patient's quality of life. This study aimed to examine how …
Mesenchymal stem cell derived exosomes suppress neuronal cell ferroptosis via lncGm36569/miR-5627-5p/FSP1 axis in acute spinal cord injury
C Shao, Y Chen, T Yang, H Zhao, D Li - Stem Cell Reviews and Reports, 2022 - Springer
Exosomes derived from mesenchymal stem cells (MSCs) have been considered as an
alternative for cell therapy of acute spinal cord injury (ASCI). However, the underlying …
alternative for cell therapy of acute spinal cord injury (ASCI). However, the underlying …
Exosomes secreted by hypoxia–pre-conditioned adipose-derived mesenchymal stem cells reduce neuronal apoptosis in rats with spinal cord injury
Y Liang, JH Wu, JH Zhu, H Yang - Journal of neurotrauma, 2022 - liebertpub.com
Neuronal death is the main cause of nerve function impairment after spinal cord injury (SCI).
Exosome-based therapy has become a novel strategy for tissue injury repair. We designed a …
Exosome-based therapy has become a novel strategy for tissue injury repair. We designed a …
Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after …
J Ren, B Zhu, G Gu, W Zhang, J Li, H Wang… - Cell death & …, 2023 - nature.com
Macrophage/microglia polarization acts as an important part in regulating inflammatory
responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann …
responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann …
Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis
D Zhong, Y Cao, CJ Li, M Li, ZJ Rong… - Experimental …, 2020 - journals.sagepub.com
Acute traumatic spinal cord injury is a devastating event without effective therapeutic
approach. The feeble plasticity of spinal cord microvascular endothelial cells (SCMECs) …
approach. The feeble plasticity of spinal cord microvascular endothelial cells (SCMECs) …
[HTML][HTML] Inhibition of Ferroptosis by Mesenchymal Stem Cell-Derived Exosomes in Acute Spinal Cord Injury: Role of Nrf2/GCH1/BH4 Axis
Y Chen, B Li, J Quan, Z Li, Y Li, Y Tang - Neurospine, 2024 - ncbi.nlm.nih.gov
Objective The therapeutic benefits of exosomes obtained from mesenchymal stem cells
(MSCs) in acute spinal cord injury (SCI) have been demonstrated in recent years, but the …
(MSCs) in acute spinal cord injury (SCI) have been demonstrated in recent years, but the …
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury
F Yuan, W Peng, Y Yang, J Xu, Y Liu, Y Xie… - Journal of …, 2023 - Springer
Background Macrophage in the spinal cord injury (SCI) area imparts a chronic pro-
inflammation effect that challenges the recovery of SCI. Previously, endothelial progenitor …
inflammation effect that challenges the recovery of SCI. Previously, endothelial progenitor …
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