Recent studies have suggested benefits for time-dependent dialysate bicarbonate
concentrations (Dbic) during hemodialysis (HD). In this clinical trial, we compared for the first …

Introduction: The dialysate bicarbonate (DB) influences the acid‐base balance in dialysis
patients. Very low and high serum bicarbonate (SB) have been related with a higher …

Introduction The validity of adjusting dialysate bicarbonate based on pre‐hemodialysis (HD)
serum bicarbonate is unclear. There are no studies of the impact of dialysate sodium on …

Abstract Fresenius Medical Care's NaturaLyte dialysate has been associated with increased
risk of sudden cardiac death by causing metabolic alkalosis from its acetate content based …

An optimal dialysate bicarbonate concentration is one that prevents postdialysis alkalemia
and predialysis acidosis. The bicarbonate requirements in any patient will depend on the …

Introduction: Acidemia and alkalemia, as a result of gradual depletion of the body's buffers
followed by rapid repletion during hemodialysis (HD), are linked to adverse consequences …

In patients receiving hemodialysis, it has long been recognized that much more bicarbonate
is delivered during treatment than ultimately appears in the blood. To gain insight into this …

Objectives: To compare bicarbonate kinetics and acid base status in HD and HDF for the
same patient; and to investigate the effect of patient physiologic parameters on these …

The optimal dialysate bicarbonate concentration is one that prevents acidosis at the
beginning of the next dialysis session while avoiding postdialysis alkalosis. Few studies …

Abstract Background In the United States, hemodialysis (HD) is generally performed via a
bicarbonate dialysate. It is not known if small amounts of acid used in dialysate to buffer the …