Proteomic analysis of prostate cancer FFPE samples reveals markers of disease progression and aggressiveness

V Lygirou, K Fasoulakis, R Stroggilos, M Makridakis… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is the second most frequently diagnosed type of
cancer in men. The lack of tools for accurate risk assessment is causing over-treatment of …

Tissue proteome signatures associated with five grades of prostate cancer and benign prostatic hyperplasia

R Kawahara, S Recuero, FCS Nogueira… - …, 2019 - Wiley Online Library
The histology‐based Gleason score (GS) of prostate cancer (PCa) tissue biopsy is the most
accurate predictor of disease aggressiveness and an important measure to guide treatment …

Discovery of serum protein biomarkers for prostate cancer progression by proteomic analysis

JA Al-Ruwaili, SET Larkin, BA Zeidan… - Cancer genomics & …, 2010 - cgp.iiarjournals.org
Background: The incidence of prostate cancer (PCa) has increased in recent years due to
the aging of the population and increased testing; however, mortality rates have remained …

Tissue proteomics studies in the investigation of prostate cancer

A Mantsiou, A Vlahou, J Zoidakis - Expert Review of Proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: Prostate cancer (PCa) is one of the leading causes of death in the
male population worldwide. Various clinical samples such as urine, blood serum, and …

The role of proteomics in prostate cancer research: biomarker discovery and validation

E Pin, C Fredolini, EF Petricoin III - Clinical biochemistry, 2013 - Elsevier
PURPOSE: Prostate Cancer (PCa) represents the second most frequent type of tumor in
men worldwide. Incidence increases with patient age and represents the most important risk …

Molecular changes in tissue proteome during prostate cancer development: Proof-of-principle investigation

A Latosinska, K Davalieva, M Makridakis, W Mullen… - Diagnostics, 2020 - mdpi.com
(1) Background: Prostate cancer (PCa) is characterized by high heterogeneity. The aim of
this study was to investigate molecular alterations underlying PCa development based on …

Proteomic Analysis of Formalin-fixed Prostate Cancer Tissue* S

BL Hood, MM Darfler, TG Guiel, B Furusato… - Molecular & cellular …, 2005 - ASBMB
Proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissue would enable
retrospective biomarker investigations of this vast archive of pathologically characterized …

Quantitative mass spectrometry-based proteomic profiling for precision medicine in prostate cancer

A Flores-Morales, D Iglesias-Gato - Frontiers in oncology, 2017 - frontiersin.org
Prostate cancer (PCa) is one of the most frequently diagnosed cancer among men in the
western societies. Many PCa patients bear tumors that will not threat their lives if left …

Proteins from formalin-fixed paraffin-embedded prostate cancer sections that predict the risk of metastatic disease

JC Dunne, DS Lamb, B Delahunt, J Murray… - Clinical proteomics, 2015 - Springer
Background Prostate cancer is the most frequently diagnosed cancer in men and the third
leading cause of cancer related deaths among men living in developed countries …

Proteomics analysis of formalin fixed paraffin embedded tissues in the investigation of prostate cancer

A Mantsiou, M Makridakis, K Fasoulakis… - Journal of proteome …, 2019 - ACS Publications
Prostate cancer (PCa) is one of the leading causes of death in men worldwide. The
molecular features, associated with the onset and progression of the disease, are under …