Adenosine and adenosine receptors (ARs) are increasingly recognized as important
therapeutic targets for controlling cognition under normal and disease conditions for its dual …

Adenosine signals through four distinct G protein-coupled receptors that are located at
various synapses, cell types and brain areas. Through them, adenosine regulates …

Introduction 3. Basic aspects of adenosine as a neuromodulator relevant for cognitive
functions 4. Effects of adenosine receptor antagonists on cognitive deficits in aged rodents …

The adenosine A2A receptor (A2AR) is in the center of a neuromodulatory network affecting
a wide range of neuropsychiatric functions by interacting with and integrating several …

Alzheimer's disease (AD) is a neurodegenerative disorder of the central nervous system
manifested by cognitive and memory deterioration, a variety of neuropsychiatric symptoms …

Alzheimer's disease (AD) is the most prevalent kind of dementia with roughly 135 million
cases expected in the world by 2050. Unfortunately, current medications for the treatment of …

This review summarizes recent developments that have contributed to understand how
adenosine receptors, particularly A2A receptors, modulate brain injury in various animal …

Endogenous adenosine is a widely distributed upstream regulator of a broad spectrum of
neurotransmitters, receptors, and signaling pathways that converge to contribute to the …

The neuromodulator adenosine fulfills a unique role in the brain affecting glutamatergic
neurotransmission and dopaminergic signaling via activation of adenosine A1 and A2A …

Adenosine A2A receptors (A2AR) are a sub-type of receptors enriched in basal ganglia,
activated by the neuromodulator adenosine, which interact with dopamine D2 receptors …