Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

AC Afonso, D Oliveira, MJ Saavedra, A Borges… - International journal of …, 2021 - mdpi.com
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Alternative approaches for the management of diabetic foot ulcers

C Pouget, C Dunyach-Remy, A Pantel… - Frontiers in …, 2021 - frontiersin.org
Diabetic foot ulcers (DFU) represent a growing public health problem. The emergence of
multidrug-resistant (MDR) bacteria is a complication due to the difficulties in distinguishing …

Microscopy visualisation confirms multi‐species biofilms are ubiquitous in diabetic foot ulcers

K Johani, M Malone, S Jensen, I Gosbell… - International wound …, 2017 - Wiley Online Library
Increasing evidence within the literature has identified the presence of biofilms in chronic
wounds and proposed that they contribute to delayed wound healing. This research aimed …

Polymicrobial biofilms by diabetic foot clinical isolates

C Mottola, JJ Mendes, JM Cristino, P Cavaco-Silva… - Folia microbiologica, 2016 - Springer
Diabetes mellitus is a major chronic disease that continues to increase significantly. One of
the most important and costly complications of diabetes is foot ulceration that may be …

The diabetic foot: the importance of biofilms and wound bed preparation

SC Davis, L Martinez, R Kirsner - Current diabetes reports, 2006 - Springer
Biofilms are ubiquitous and medically important complex structures consisting of microbial-
associated cells embedded in self-produced extracellular matrix of hydrated extrapolymeric …

Diabetes and foot infection: more than double trouble

JL Richard, JP Lavigne, A Sotto - … /Metabolism Research and …, 2012 - Wiley Online Library
Background Infection of foot ulcers is a common, often severe and costly complication in
diabetes. Many factors linked to the host, mainly immune defects, neuropathy and …

Diabetic foot infection: A critical complication

JJ Hurlow, GJ Humphreys, FL Bowling… - International wound …, 2018 - Wiley Online Library
The number of people in the world with diabetes has nearly quadrupled in the past 40 years.
Current data show that 25% of these diabetics will develop a foot ulcer in their lifetime and …

Role of anaerobes in polymicrobial communities and biofilms complicating diabetic foot ulcers

SL Percival, M Malone, D Mayer… - International wound …, 2018 - Wiley Online Library
Infected tissues in the feet of people with diabetes in the form of a diabetic foot ulcer (DFU)
present a complex pathology for clinicians to manage. This is partly attributed to the multi …

New molecular techniques to study the skin microbiota of diabetic foot ulcers

JP Lavigne, A Sotto, C Dunyach-Remy… - Advances in wound …, 2015 - liebertpub.com
Significance: Diabetic foot ulcers (DFU) are a major and growing public health problem.
They pose difficulties in clinical practice in both diagnosis and management. Bacterial …