Bacterial chromosomes are folded to compact DNA and facilitate cellular processes.
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …

All viable bacterial cells, whether they divide symmetrically or asymmetrically, must
coordinate their growth, division, cell volume and shape with the inheritance of the genome …

Since the nucleoid was isolated from bacteria in the 1970s, two fundamental questions
emerged and are still in the spotlight: how bacteria organize their chromosomes to fit inside …

If fully stretched out, a typical bacterial chromosome would be nearly 1 mm long,
approximately 1,000 times the length of a cell. Not only must cells massively compact their …

Bacterial genomes are functionally organized and compactly folded into a structure referred
to as bacterial chromatin or the nucleoid. An important role in genome folding is attributed to …

Recent advances in bacterial cell biology have revealed unanticipated structural and
functional complexity, reminiscent of eukaryotic cells. Particular progress has been made in …

Genome architecture has proven to be critical in determining gene regulation across almost
all domains of life. While many of the key components and mechanisms of eukaryotic …

The bacterial genome is folded into a compact structure called the nucleoid. Considerable
compaction of the DNA molecule is required in order to reduce its volume below that of the …

Many bacterial cellular processes interact intimately with the chromosome. Such interplay is
the major driving force of genome structure or organization. Interactions take place at …

The genomic DNA of all organisms across the three kingdoms of life needs to be compacted
and functionally organized. Key players in these processes are DNA supercoiling …