Importance For more than a decade, sorafenib has been the only systemic treatment option
for patients with advanced hepatocellular carcinoma (HCC). However, rapid progress over …

Hepatocellular carcinoma (HCC) is one of most common cancers and the fourth leading
cause of death worldwide. Commonly, HCC development occurs in a liver that is severely …

Introduction Immunotherapy has recently taken on an extremely important role in medical
oncology, as first-or later-line treatment in several tumor types, and recent years have seen …

Hepatocellular carcinoma (HCC) is an important cause of cancer death and is considered
the 3rd most lethal around the world. Hepatectomy, liver transplantation, and ablation …

Hepatocellular carcinoma (HCC) is the second deadliest cancer worldwide, due to its high
incidence and poor prognosis. Frequent initial presentation at advanced stages along with …

Hepatocellular carcinoma (HCC) is usually diagnosed in an advanced stage and has
become the second deadliest type of cancer worldwide. The systemic treatment of advanced …

Immune checkpoint blockade has recently emerged as a promising therapeutic approach for
various malignancies including hepatocellular carcinoma (HCC). Preclinical and clinical …

The discovery of the immune checkpoint mechanism has contributed greatly to recent
advances in cancer treatment. The anticytotoxic T lymphocyte-associated protein 4 antibody …

Simple Summary Immune checkpoint inhibitors represent a promising treatment choice in
many kind of tumours, including hepatocellular carcinoma (HCC). In this review, we provide …

The position of immunotherapy as a pillar of systemic cancer treatment has been firmly
established over the past decade. Immune checkpoint inhibitors are a welcome option for …