Calcium is the most abundant metabolite involved in the stone matrix. The CaSR gene
controls calcium homeostasis, and genetic variation in the CaSR gene could lead to the …

Background: CaSR gene is a candidate for calcium nephrolithiasis. Single-nucleotide
polymorphisms (SNPs) encompassing its regulatory region were associated with calcium …

Calcium (Ca) stone is a common problem related to abnormal calcium biometabolism. The
calcium stone is known to be associated with the nephrolithiasis-related end-stage renal …

Calcium nephrolithiasis is one of the most common causes of renal stones. While the
prevalence of this disease has increased steadily over the last 3 decades, its pathogenesis …

Background. The calcium-sensing receptor gene (CaSR) is a candidate to explain
urolithiasis. A number of case-control studies were conducted to investigate associations …

Genetic polymorphism (rs6776158) in CaSR gene is associated... : Medicine Genetic
polymorphism (rs6776158) in CaSR gene is associated with risk of nephrolithiasis in …

The calcium‐sensing receptor (CaSR) gene plays an important role in regulating the Ca2+
balance and reducing the risk for calcium stones. In this study, we evaluated the association …

Background Nephrolithiasis (NL) affects 1 in 11 individuals worldwide and causes
significant morbidity and cost. Common variants in the calcium sensing receptor gene …

Calcium-sensing receptor (CaSR) is a plasma-membrane G protein-coupled receptor
activated by extracellular calcium and expressed in kidney tubular cells. It inhibits calcium …

Background: Calcium oxalate nephrolithiasis may be considered as a complex disease
having multiple pathogenetic mechanisms. Calcium homeostasis is crucially regulated by …