Genome-wide association studies (GWASs) have identified many SNPs underlying
variations in plasma-lipid levels. We explore whether additional loci associated with plasma …

For the past five years, genome-wide association studies (GWAS) have identified hundreds
of common variants associated with human diseases and traits, including high-density …

Plasma lipid levels are important risk factors for cardiovascular disease and are influenced
by genetic and environmental factors. Recent genome wide association studies (GWAS) …

We performed genome-wide meta-analysis of lipid traits on three samples of Mexican and
Mexican American ancestry comprising 4,383 individuals and followed up significant and …

Background Blood lipid levels including low-density lipoprotein cholesterol (LDL-C), high-
density lipoprotein cholesterol (HDL-C), and triglycerides (TG) are highly heritable. Genome …

Background—Using the genome-wide association approach in individuals of European
ancestry, we and others recently identified single-nucleotide polymorphisms (SNPs) at 19 …

A major challenge of genome-wide association studies (GWASs) is to translate phenotypic
associations into biological insights. Here, we integrate a large GWAS on blood lipids …

Background Genetic variants within nearly 1000 loci are known to contribute to modulation
of blood lipid levels. However, the biological pathways underlying these associations are …

Blood lipid concentrations are heritable risk factors associated with atherosclerosis and
cardiovascular diseases. Lipid traits exhibit considerable variation among populations of …

Most genome-wide association studies (GWAS) for lipid traits focus on the separate analysis
of lipid traits. Moreover, there are limited GWASs evaluating the genetic variants associated …