We describe herein an intriguing method for the synthesis of biaryl aldehydes bearing both
axial and central chirality through a desymmetric [3+ 2] cycloaddition reaction of activated …

Diaryl ethers are important structural motifs widely found in bioactive natural products,
ligands, and catalysts. While there are a variety of methods available to generate diaryl …

A highly enantioselective copper-catalyzed [3+ 2] cycloaddition reaction of α-isocyanoesters
with β, β-disubstituted enones has been developed. Dihydropyrroles were obtained in …

The copper-catalyzed enantioselective C–H arylation between 2-arylindoles and
hypervalent iodine reagents has been successfully developed, which provides a convenient …

We have developed a new umpolung strategy for catalytically forming a chiral α-alkoxyalkyl
anion from an aromatic aldehyde for use in asymmetric synthesis. The reaction between …

A highly selective and practical asymmetric Ag (I) catalyst system has been developed for
the [3+ 2] cycloaddition reactions between isocyanoacetates and cyclopentenediones. The …

Comprehensive Summary Transition‐metal‐catalyzed asymmetric alkylation of aldehydes
represents a straightforward strategy for the synthesis of chiral secondary alcohols …

Heterocyclic compounds containing a chiral pyrrolidine motif commonly appear in natural
alkaloids and pharmaceutically active substances, and serve as building blocks commonly …

A highly enantioselective desymmetrization of prochiral cyclopentenediones via Ag (I)-
catalyzed asymmetric 1, 3-dipolar cycloaddition of azomethine ylide has been developed …

Since the early reports on catalytic enantioselective diethylzinc additions, 1 the asymmetric
reaction of aldehydes with dialkylzinc reagents has been studied very extensively. 2, 3 A …