The traditional Japanese herbal medicine hangeshashinto (HST) has beneficial effects for
the treatment of oral ulcerative mucositis (OUM) in cancer patients. However, the ingredient …

Background Oral ulcerative mucositis causes severe pain during eating and speaking,
resulting in poor quality of life for patients with cancer undergoing chemoradiotherapy …

Objective Recent studies have demonstrated that mouthwash made with the traditional
Japanese medicine hangeshashinto exhibits anti-inflammatory action and alleviates oral …

Ethnopharmacology relevance Pain often causes a series of abnormal changes in
physiology and psychology, which can lead to disease and even death. Drug therapy is the …

Glycyrrhiza extract has been used for the treatment of oral and gastric ulcers, but the
analgesic mechanism remains unknown. In the present study, we investigated the effects of …

This article highlights several refractory oral diseases, such as stomatitis, burning mouth
syndrome (BMS), glossalgia, atypical facial pain (AFP), oral cancer, dry mouth, and …

Shaoyao-Gancao Tang (SGT) is one of the most frequently used compound formulas in the
treatment of pain-related diseases in the medical practice of traditional Chinese medicine …

Background Ginseng saponin has long been used as a traditional Asian medicine and is
known to be effective in treating various kinds of pain. Ginsenoside Rf is one of the …

The present study was designed to search for compounds with analgesic activity from the
Schizophyllum commune (SC), which is widely consumed as edible and medicinal …

Oren-gedoku-to and Unsei-in are complex mixtures of ingredients derived from plants.
These two drugs are clinically most frequently used in the treatment of Behçet's disease, we …