Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles
C Schoch, A Kohlmann, S Schnittger… - Proceedings of the …, 2002 - National Acad Sciences
Acute myeloid leukemia (AML) is a heterogeneous group of genetically defined diseases.
Their classification is important with regard to prognosis and treatment. We performed …
Their classification is important with regard to prognosis and treatment. We performed …
Genome‐wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation …
S Debernardi, DM Lillington, T Chaplin… - Genes …, 2003 - Wiley Online Library
Gene expression profiles were determined from presentation peripheral blood and bone
marrow samples of 28 patients with acute myeloid leukemia (AML). Hierarchical clustering …
marrow samples of 28 patients with acute myeloid leukemia (AML). Hierarchical clustering …
[HTML][HTML] Prognostically useful gene-expression profiles in acute myeloid leukemia
PJM Valk, RGW Verhaak, MA Beijen… - … England Journal of …, 2004 - Mass Medical Soc
Background In patients with acute myeloid leukemia (AML) a combination of methods must
be used to classify the disease, make therapeutic decisions, and determine the prognosis …
be used to classify the disease, make therapeutic decisions, and determine the prognosis …
[PDF][PDF] Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization
FG Rücker, L Bullinger, C Schwaenen, DB Lipka… - J Clin Oncol, 2006 - Citeseer
Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using
Microarray-Based Molecular Characterizatio Page 1 Disclosure of Candidate Genes in Acute …
Microarray-Based Molecular Characterizatio Page 1 Disclosure of Candidate Genes in Acute …
Cytogenetics in acute myeloid leukemia
C Schoch, T Haferlach - Current oncology reports, 2002 - Springer
Cytogenetic analysis is the most important diagnostic tool for determining prognosis in acute
myeloid leukemia (AML). In the majority of patients with AML, acquired clonal chromosome …
myeloid leukemia (AML). In the majority of patients with AML, acquired clonal chromosome …
AML with translocation t (8; 16)(p11; p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features
T Haferlach, A Kohlmann, HU Klein, C Ruckert… - Leukemia, 2009 - nature.com
Balanced chromosomal rearrangements define distinct entities in acute myeloid leukemia
(AML). Here, we present 13 AML cases with t (8; 16)(p11; p13) with observed low incidence …
(AML). Here, we present 13 AML cases with t (8; 16)(p11; p13) with observed low incidence …
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
A Dolnik, JC Engelmann… - Blood, The Journal …, 2012 - ashpublications.org
Acute myeloid leukemia (AML) is characterized by molecular heterogeneity. As commonly
altered genomic regions point to candidate genes involved in leukemogenesis, we used …
altered genomic regions point to candidate genes involved in leukemogenesis, we used …
Gene expression profiling in acute myeloid leukemia
L Bullinger, PJM Valk - Journal of Clinical Oncology, 2005 - ascopubs.org
Over the last decades, significant advances have been made in the knowledge and
treatment of acute myeloid leukemia (AML). The WHO has recognized this new information …
treatment of acute myeloid leukemia (AML). The WHO has recognized this new information …
[HTML][HTML] Molecular characterization of acute myeloid leukemia
K Döhner, H Döhner - Haematologica, 2008 - haematologica.org
Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized
by the accumulation of acquired somatic genetic alterations in hematopoietic progenitor …
by the accumulation of acquired somatic genetic alterations in hematopoietic progenitor …
Incidence of chromosome abnormalities and clinical significance of karyotype in de novo acute myeloid leukemia
R Stasi, G Del Poeta, M Masi, M Tribalto… - Cancer genetics and …, 1993 - Elsevier
Cytogenetic studies with high-resolution banding were performed on specimens from 132
consecutive patients with de novo acute myeloid leukemia (AML). All patients were treated …
consecutive patients with de novo acute myeloid leukemia (AML). All patients were treated …