Potential biomarkers for immunotherapy in non-small-cell lung cancer

X Wang, Z Qiao, B Aramini, D Lin, X Li, J Fan - Cancer and Metastasis …, 2023 - Springer
For individuals with advanced or metastatic non-small cell lung cancer (NSCLC), the primary
treatment is platinum-based doublet chemotherapy. Immune checkpoint inhibitors (ICIs) …

Predictive biomarkers for immunotherapy efficacy in non-small-cell lung cancer: current status and future perspectives

DC Guven, TK Sahin, O Dizdar… - Biomarkers in medicine, 2020 - Taylor & Francis
In recent years, immune checkpoint inhibitors have rapidly changed treatment paradigms
and have been pivotal for the treatment of advanced NSCLC patients. However, many …

Advances in Biomarkers for Immunotherapy of Non-small Cell Lung Cancer.

C Huang, Y Xue - Chinese Journal of Lung Cancer, 2021 - search.ebscohost.com
Lung cancer is a malignant tumor with the highest mortality in the world. The most common
pathological type of lung cancer is non-small cell lung cancer (NSCLC). In recent years …

Choosing the optimal immunotherapeutic strategies for non-small cell lung cancer based on clinical factors

N Nakagawa, M Kawakami - Frontiers in oncology, 2022 - frontiersin.org
The treatment landscape of advanced non-small cell lung cancer (NSCLC) has changed
dramatically since the emergence of immune checkpoint inhibitors (ICIs). Although some …

Immunotherapy in non-small cell lung cancer: rationale, recent advances and future perspectives

W Luo, Z Wang, T Zhang, L Yang, J Xian… - Precision clinical …, 2021 - academic.oup.com
Lung cancer, with non-small cell lung cancer (NSCLC) being the major type, is the second
most common malignancy and the leading cause of cancer-related death globally …

Gene expressions and high lymphocyte count may predict durable clinical benefits in patients with advanced non-small-cell lung cancer treated with immune …

MT Mouritzen, M Ladekarl, H Hager, TB Mattesen… - Cancers, 2023 - mdpi.com
Simple Summary Despite the promising results not all patients with advanced non-small cell
lung cancer benefit from immunotherapy. Immunotherapy may cause severe adverse …

Recognizing prognostic and predictive biomarkers in the treatment of non-small cell lung cancer (NSCLC) with immune checkpoint inhibitors (ICIs)

N Giustini, L Bazhenova - Lung Cancer: Targets and Therapy, 2021 - Taylor & Francis
Immunotherapy plays a central role in the treatment of NSCLC and biomarkers predicting
response to ICIs are valuable therapeutic tools. Programmed death-ligand 1 (PD-L1) …

Predictive biomarkers for immunotherapy in lung cancer: perspective from the international association for the study of lung cancer pathology committee

M Mino-Kenudson, K Schalper, W Cooper… - Journal of Thoracic …, 2022 - Elsevier
Immunotherapy including immune checkpoint inhibitors (ICIs) has become the backbone of
treatment for most lung cancers with advanced or metastatic disease. In addition, they have …

Biomarkers of immunotherapy in non‑small cell lung cancer

L Wang, Y Hu, S Wang, J Shen… - Oncology …, 2020 - spandidos-publications.com
Immunotherapy has markedly improved the survival rate of patients with non‑small cell lung
cancer (NSCLC) and has introduced a new era in lung cancer treatment. However, not all …

Biomarkers of Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer: Beyond PD-L1

L Cabezon-Gutierrez, S Custodio-Cabello… - Clinical Lung Cancer, 2021 - Elsevier
Immunotherapy has markedly improved the survival rate of patients with non–small cell lung
cancer (NSCLC) and has introduced a new era in lung cancer treatment. Although some …