The genome landscape of the african green monkey kidney-derived vero cell line
N Osada, A Kohara, T Yamaji, N Hirayama… - DNA …, 2014 - academic.oup.com
Continuous cell lines that originate from mammalian tissues serve as not only invaluable
tools for life sciences, but also important animal cell substrates for the production of various …
tools for life sciences, but also important animal cell substrates for the production of various …
[HTML][HTML] A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys
J Qu, F Yang, T Zhu, Y Wang, W Fang, Y Ding… - Nature …, 2022 - nature.com
Non-human primates are attractive laboratory animal models that accurately reflect both
developmental and pathological features of humans. Here we present a compendium of cell …
developmental and pathological features of humans. Here we present a compendium of cell …
[HTML][HTML] Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
The nonhuman primates most commonly used in medical research are from the genus
Macaca. To better understand the genetic differences between these animal models, we …
Macaca. To better understand the genetic differences between these animal models, we …
[HTML][HTML] Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome
Chinese hamster ovary (CHO) cells, first isolated in 1957, are the preferred production host
for many therapeutic proteins. Although genetic heterogeneity among CHO cell lines has …
for many therapeutic proteins. Although genetic heterogeneity among CHO cell lines has …
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility
INTRODUCTION The rhesus macaque (Macaca mulatta) is one of the most widely used
nonhuman primate (NHP) models for studying human biology and disease. As a …
nonhuman primate (NHP) models for studying human biology and disease. As a …
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
S Metsuyanim, N Pode-Shakked, KM Schmidt-Ott… - Stem Cells, 2008 - academic.oup.com
Recent studies indicate a dual epigenetic role of the Polycomb group (PcG) proteins in self-
renewal of stem cells and oncogenesis. Their elevation in our previous human kidney …
renewal of stem cells and oncogenesis. Their elevation in our previous human kidney …
HEK293 in cell biology and cancer research: phenotype, karyotype, tumorigenicity, and stress-induced genome-phenotype evolution
AA Stepanenko, VV Dmitrenko - Gene, 2015 - Elsevier
Abstract 293 cell line (widely known as the Human Embryonic Kidney 293 cells) and its
derivatives were the most used cells after HeLa in cell biology studies and after CHO in …
derivatives were the most used cells after HeLa in cell biology studies and after CHO in …
[HTML][HTML] Comparative epigenomic annotation of regulatory DNA
Despite the explosive growth of genomic data, functional annotation of regulatory
sequences remains difficult. Here, we introduce" comparative epigenomics"—interspecies …
sequences remains difficult. Here, we introduce" comparative epigenomics"—interspecies …
[HTML][HTML] Structurally divergent and recurrently mutated regions of primate genomes
Y Mao, WT Harvey, D Porubsky, KM Munson… - Cell, 2024 - cell.com
We sequenced and assembled using multiple long-read sequencing technologies the
genomes of chimpanzee, bonobo, gorilla, orangutan, gibbon, macaque, owl monkey, and …
genomes of chimpanzee, bonobo, gorilla, orangutan, gibbon, macaque, owl monkey, and …
The genomic and transcriptomic landscape of a HeLa cell line
HeLa is the most widely used model cell line for studying human cellular and molecular
biology. To date, no genomic reference for this cell line has been released, and experiments …
biology. To date, no genomic reference for this cell line has been released, and experiments …