[HTML][HTML] Quadrupole time-of-flight mass spectrometry: a paradigm shift in toxicology screening applications

DR Allen, BC McWhinney - The Clinical Biochemist Reviews, 2019 - ncbi.nlm.nih.gov
The screening of biological samples for the presence of illicit or legal substances is an
important frontline tool in both clinical and forensic toxicology. In the clinical setting, drug …

Perspectives of liquid chromatography coupled to low-and high-resolution mass spectrometry for screening, identification, and quantification of drugs in clinical and …

HH Maurer - Therapeutic drug monitoring, 2010 - journals.lww.com
This article reviews papers on the use of liquid chromatography coupled to low-and high-
resolution mass spectrometry in clinical and forensic toxicology. They cover procedures for …

Quantitative liquid chromatography/time‐of‐flight mass spectrometry

LN Williamson, MG Bartlett - Biomedical Chromatography, 2007 - Wiley Online Library
Over the last decade, time‐of‐flight (TOF) instruments have increasingly been used as
quantitation tools. In addition, because of their high resolving power, they can be used for …

Current applications of high-resolution mass spectrometry for the analysis of new psychoactive substances: a critical review

D Pasin, A Cawley, S Bidny, S Fu - Analytical and bioanalytical chemistry, 2017 - Springer
The proliferation of new psychoactive substances (NPS) in recent years has resulted in the
development of numerous analytical methods for the detection and identification of known …

Validation of LC–TOF-MS screening for drugs, metabolites, and collateral compounds in forensic toxicology specimens

F Guale, S Shahreza, JP Walterscheid… - Journal of analytical …, 2013 - academic.oup.com
Liquid chromatography time-of-flight mass spectrometry (LC–TOF-MS) analysis provides an
expansive technique for identifying many known and unknown analytes. This study …

Recent advances of liquid chromatography–(tandem) mass spectrometry in clinical and forensic toxicology—an update

D Remane, DK Wissenbach, FT Peters - Clinical biochemistry, 2016 - Elsevier
Liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass
spectrometry (MS/MS) is a well-established and widely used technique in clinical and …

High-resolution mass spectrometry in toxicology: current status and future perspectives

HH Maurer, MR Meyer - Archives of Toxicology, 2016 - Springer
This paper reviews high-resolution mass spectrometry (HRMS) approaches using time-of-
flight or Orbitrap techniques for research and application in various toxicology fields …

Recent advances of liquid chromatography–(tandem) mass spectrometry in clinical and forensic toxicology

FT Peters - Clinical biochemistry, 2011 - Elsevier
Liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass
spectrometry (MS/MS) has become increasingly important in clinical and forensic toxicology …

Advances in drugs of abuse testing

K Tamama - Clinica Chimica Acta, 2021 - Elsevier
Drugs of abuse testing is widely used clinically and forensically. Urine is the preferred type
of specimen for drugs of abuse screening, but saliva, sweat, hair, and meconium are …

Direct Analysis in Real Time (DART) and a portable mass spectrometer for rapid identification of common and designer drugs on-site

H Brown, B Oktem, A Windom, V Doroshenko… - Forensic Chemistry, 2016 - Elsevier
Identification and differentiation of the consistently evolving designer drugs being
encountered by law enforcement is challenging established techniques in drug analysis. We …