[HTML][HTML] Innate Immunity Focus: Role of adipose tissue macrophages in obesity-related disorders
The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …
Adipose tissue macrophages as potential targets for obesity and metabolic diseases
X Li, Y Ren, K Chang, W Wu, HR Griffiths, S Lu… - Frontiers in …, 2023 - frontiersin.org
Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose
tissue dysfunction and contributing to obesity-induced inflammation and metabolic …
tissue dysfunction and contributing to obesity-induced inflammation and metabolic …
Defining macrophage phenotype and function in adipose tissue
E Dalmas, K Clément, M Guerre-Millo - Trends in immunology, 2011 - cell.com
In obesity, chronic low-grade inflammation is thought to mediate the effects of increased
adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to …
adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to …
New insights into adipose tissue macrophages in obesity and insulin resistance
Z Cai, Y Huang, B He - Cells, 2022 - mdpi.com
Obesity has become a worldwide epidemic that poses a severe threat to human health.
Evidence suggests that many obesity comorbidities, such as type 2 diabetes mellitus …
Evidence suggests that many obesity comorbidities, such as type 2 diabetes mellitus …
Innate immune control of adipose tissue homeostasis
Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …
Recently, the immune system has been implicated in the regulation of adipose tissue …
Adipose tissue macrophages: going off track during obesity
L Boutens, R Stienstra - Diabetologia, 2016 - Springer
Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …
forces for the development of insulin resistance and type 2 diabetes in obese individuals …
Macrophages, immunity, and metabolic disease
JC McNelis, JM Olefsky - Immunity, 2014 - cell.com
Chronic, low-grade adipose tissue inflammation is a key etiological mechanism linking the
increasing incidence of type 2 diabetes (T2D) and obesity. It is well recognized that the …
increasing incidence of type 2 diabetes (T2D) and obesity. It is well recognized that the …
Macrophage and T cell networks in adipose tissue
RD Jacks, CN Lumeng - Nature Reviews Endocrinology, 2024 - nature.com
The signals and structure of the tissues in which leukocytes reside critically mould leukocyte
function and development and have challenged our fundamental understanding of how to …
function and development and have challenged our fundamental understanding of how to …
[HTML][HTML] Innate immune cells in the adipose tissue in health and metabolic disease
Z Michailidou, M Gomez-Salazar… - Journal of innate immunity, 2022 - karger.com
Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …
Adipose tissue macrophages and their polarization in health and obesity
L Catrysse, G van Loo - Cellular immunology, 2018 - Elsevier
Adipose tissue is a special tissue environment due to its high lipid content. Adipose tissue
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …