Cytomegalovirus is transmitted with blood and organs from seropositive individuals,
although the particular leukocyte population harboring latent or persistent virus remains …

Monocytes are one of the predominant cell types in the peripheral blood that are infected by
human cytomegalovirus (HCMV). Although virus can be detected in these cells in vivo …

On the basis of in vitro experiments, it has been suggested that cells of hematopoietic origin
play a major role in the pathogenesis and latency of human cytomegalovirus (HCMV). To …

A distinctive feature of the cytomegaloviruses is their wide tissue tropism, demonstrated by
the infection of many organs and cell types in an active infection. However, in experimental …

Hematopoietic cells and their progenitors play important roles in human cytomegalovirus
latency and reactivation. Latent infection has been evaluated in defined populations of …

Stimulation of monocytes/macrophages with activated nonadherent cells allows productive
nonlytic growth of human cytomegalovirus (HCMV), but the viral replication cycle is delayed …

Human cytomegalovirus (HCMV) can be isolated from peripheral blood leukocytes;
however, in vitro, only abortive infection of monocytes, lymphocytes, and granulocytes has …

Circulating leukocytes are important in dissemination of cytomegalovirus (CMV) infection in
humans. In the mouse model of murine CMV infection (MCMV), it has been shown that …

Blood monocytes or tissue macrophages play a pivotal role in the pathogenesis of murine
cytomegalovirus (MCMV) infection, providing functions beneficial to both the virus and the …

Monocytes differentiated in the presence of phytohemagglutinin P-stimulated T cells could
be infected with human cytomegalovirus AD169 and produced low levels of infectious virus …