Bioorthogonal transition metal catalysts (TMCs) transform therapeutically inactive molecules
(pro-drugs) into active drug compounds. Inorganic nanoscaffolds protect and solubilize …

Bioorthogonal chemistry refers to any chemical reactions that can occur inside of living
systems without interfering with native biochemical processes, which has become a …

Bioorthogonal transformations are chemical reactions that use pathways which biological
processes do not access. Bioorthogonal chemistry provides new approaches for imaging …

Transition metal catalysts (TMCs), capable of performing bioorthogonal reactions, have
been engineered to trigger the formation of bioactive molecules in a controlled manner for …

Bioorthogonal catalysis using transition-metal-based complexes (TMCs) is a promising
approach for converting substrates to desired products in complex cellular media. Notably …

Bioorthogonal catalysis using transition-metal catalysts (TMCs) provides a toolkit for the in
situ generation of imaging and therapeutic agents in biological environments. Integrating …

Bioorthogonal catalysis via transition metal catalysts (TMCs) enables the generation of
therapeutics locally through chemical reactions not accessible by biological systems. This …

Bioorthogonal catalysis mediated by transition metal catalysts (TMCs) provides controlled in
situ activation of prodrugs through chemical reactions that do not interfere with cellular …

In the past two decades, bio-orthogonal transformations mediated by biocompatible metal
catalysts in living systems have shown enormous potential in both synthetic biology and …

Bioorthogonal catalysis offers a unique strategy to modulate biological processes through
the in situ generation of therapeutic agents. However, the direct application of bioorthogonal …