The importance of Müller glia for retinal homeostasis suggests that they may have
vulnerabilities that lead to retinal disease. Here, we studied the effect of selectively knocking …

Photoreceptor degeneration caused by genetic defects leads to retinitis pigmentosa, a rare
disease typically diagnosed in adolescents and young adults. In most cases, rod loss occurs …

Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor
loss, which induces concomitant changes in the neural retina, one of the most striking being …

Retinal neurons and Müller glia are generated from a common population of multipotent
retinal progenitor cells. We purposed to identify Müller glia-specific molecular signatures …

Glia‐neuron partnership is important for inner retinal homeostasis and any disturbances
may result in retinal ganglion cell (RGC) death. Müller cells support RGCs with essential …

Müller cell is the most abundant glial cell in mammalian retina, supporting the functions of
photoreceptors and other retinal neurons via maintaining environmental homeostasis. In …

Müller glia are the principal macroglia of the retina and support retinal neurons both in
health and disease. In retinitis pigmentosa (RP), a highly heterogeneous inherited retinal …

A striking aspect of tissue regeneration is its uneven distribution among different animal
classes, both in terms of modalities and efficiency. The retina does not escape the rule …

Retinal Müller glial cells (MGs) are among the first to demonstrate metabolic changes during
retinal disease and are a potential source of regenerative cells. In response to a harmful …

The purpose of this study was to investigate whether insulin, fibroblast growth factor (FGF),
and mitogen-activated protein kinase (MAPK) pathways protect retinal neurons against …