(1) Background: Doxorubicin (DOX) is extensively used for cancer treatments; however, its
clinical application is limited because of its cardiotoxic adverse effects. A combination of …

Although doxorubicin (DOX) is an efficient chemotherapeutic drug for human tumors, severe
cardiotoxicity restricts its clinical use. Cinnamaldehyde (CA), a bioactive component isolated …

Background As one of the most classic antineoplastic agents, doxorubicin (Dox) is
extensively used to treat a wide range of cancers. Nevertheless, the clinical outcomes of Dox …

Doxorubicin (DOX)‐induced cardiomyopathy is a lethal disease. DOX‐induced cardiotoxic
effects are attributed towards increased redox status and apoptotic signaling. In this study …

This work aimed to reveal the protective mechanism of CA against Dox (doxorubicin)-
induced cardiotoxicity. In isolated murine cardiomyocytes, CA showed a concentration …

Doxorubicin‐induced cardiotoxicity is the leading cause of morbidity and mortality among
cancer survivors. The present study was aimed to investigate the cardioprotective potential …

OBJECTIVE: Doxorubicin (DOX) is an effective chemotherapeutic agent used in the
treatment of various neoplasms. Nevertheless, its therapeutic efficacy is hampered by life …

Despite the effectiveness of doxorubicin (DOX) in the management of a wide range of
cancers, a major challenge is its cardio-toxic effect. Oxidative stress, inflammation, and …

Although doxorubicin (DOX) is among the most widely used anticancer agents, its clinical
application is hampered owing to its cardiotoxicity. Adjuvant therapy with an antioxidant has …

Choline is a precursor of the major neurotransmitter acetylcholine and has been
demonstrated beneficial in diverse models of cardiovascular disease. Here, we sought to …