In a relatively short period of time, treatment strategies for metastatic melanoma have
radically changed leading to an unprecedented improvement in patient survival. In this …

The recent emergence of cancer immunotherapies initiated a significant shift in the clinical
management of metastatic melanoma. Prior to 2011, melanoma patients only had palliative …

Metastatic melanoma was the first malignancy in which immune checkpoint inhibitors
demonstrated their successful efficacy. Currently, the knowledge on the interaction between …

Melanoma has always been described as an immunogenic tumor. Despite that, until 2011
the standard of care in metastatic melanoma was chemotherapy, with low response rates …

In recent years, the introduction and Federal Drug Administration approval of immune
checkpoint inhibitor antibodies has dramatically improved the clinical outcomes for patients …

Melanoma is the most fatal skin cancer. In the early stages, it can be safely treated with
surgery alone. However, since 2011, there has been an important revolution in the treatment …

Melanoma is the deadliest form of skin cancer and has an incidence that is rising faster than
any other solid tumor. Metastatic melanoma treatment has considerably progressed in the …

Malignant melanoma is on the rise. There have been recent advances in targeted agents
and immunotherapies that have improved the management and treatment of patients with …

Importance In recent years, the management of metastatic melanoma has been transformed
by the emergence of immune checkpoint inhibitors and targeted therapies that significantly …

The incidence of melanoma has been increasing over the past twenty years. Unfortunately,
the prognosis of advanced-stage disease is still poor. Advances have been made in the …