[HTML][HTML] miR-223: an effective regulator of immune cell differentiation and inflammation

P Jiao, XP Wang, ZM Luoreng, J Yang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) play a critical role in regulating various biological processes, such as
cell differentiation and immune modulation by binding to their target genes. miR-223 is a …

MicroRNA miR-223 as regulator of innate immunity

X Yuan, N Berg, JW Lee, TT Le… - Journal of leukocyte …, 2018 - academic.oup.com
MicroRNAs were discovered more than 2 decades ago and have profound impact on
diverse biological processes. Specific microRNAs have important roles in modulating the …

miR-223: an immune regulator in infectious disorders

S Yuan, Q Wu, Z Wang, Y Che, S Zheng… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are diminutive noncoding RNAs that can influence disease
development and progression by post-transcriptionally regulating gene expression. The anti …

Role of miR-223 in the pathophysiology of liver diseases

D Ye, T Zhang, G Lou, Y Liu - Experimental & molecular medicine, 2018 - nature.com
MiRNAs are small, noncoding RNAs, which can regulate gene expression
posttranscriptionally, and they have emerged as key factors in disease biology by aiding in …

The emerging role of miR-223 as novel potential diagnostic and therapeutic target for inflammatory disorders

F Aziz - Cellular immunology, 2016 - Elsevier
Since their discovery of more than a decade ago, microRNAs have been demonstrated to
have profound effects on almost every aspect of biology. Specific microRNAs have emerged …

miR-223: a key regulator in the innate immune response in asthma and COPD

MP Roffel, KR Bracke, IH Heijink, T Maes - Frontiers in medicine, 2020 - frontiersin.org
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are chronic obstructive
respiratory diseases characterized by airway obstruction, inflammation, and remodeling …

The many facets of miR‐223 in cancer: oncosuppressor, oncogenic driver, therapeutic target, and biomarker of response

A Favero, I Segatto, T Perin… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Given their intrinsic pleiotropism, microRNAs (miR) play complex biological roles, in both
normal and pathological conditions. Often the same miR can act as oncogene or …

miRNA-223 at the crossroads of inflammation and cancer

J Jeffries, W Zhou, AY Hsu, Q Deng - Cancer letters, 2019 - Elsevier
Abstract miR-223 is an evolutionarily conserved anti-inflammatory microRNA primarily
expressed in myeloid cells. miR-223 post-transcriptionally regulates many genes essential …

The role of miRNA-223 in cancer: Function, diagnosis and therapy

Y Gao, L Lin, T Li, J Yang, Y Wei - Gene, 2017 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small, non-coding RNAs with the capacity
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …

[HTML][HTML] miR-223: an inflammatory oncomiR enters the cardiovascular field

F Taïbi, V Metzinger-Le Meuth, ZA Massy… - … et Biophysica Acta (BBA …, 2014 - Elsevier
MicroRNAs (miRNAs) are small, noncoding RNAs of 18–22 nucleotides in length that
regulate post-transcriptional expression by base-pairing with target mRNAs. It is now clearly …