Chordoma is a rare bone tumor often present in the skull base and spine. In addition, it is not
sensitive to radiotherapy that surgical resection is of great significance for the treatment of …

Chordoma is a locally aggressive primary malignancy of the axial skeleton. The gold
standard for treatment is en bloc resection, with some centers now advocating for the use of …

Objectives: Chordoma is a rare bone malignancy that affects the spine and skull base.
Treatment dilemma leads to a high rate of local relapse and distant metastases. Molecular …

Background Chordoma is a rare malignant tumor of the skull base and axial skeleton, with
an incidence of less than 0.1/100,000 per year. Patients with advanced chordoma have a …

Chordoma is a very rare bone sarcoma that can arise from any site along the spine and from
the skull base. En bloc resection is the gold standard for treatment while radiation therapy …

Chordomas are rare malignant tumors arising in bone of the spheno-occiput, sacrum, and
vertebral column which can cause neurological deficit. Current management of chordoma …

Background Chordoma is a rare but devastating tumor that arises in the cranial skull base or
spine. There are currently no US Food and Drug Administration-approved targeted therapies …

Introduction Despite encouraging advances in radiation and surgical treatment, chordomas
remain resistant to chemotherapy and local recurrence is common. Although the primary …

Chordoma is a rare bony tumor, occurring across the neuraxis, most commonly in the
sacrum or skull base. Generally considered to be a malignant tumor, new evidence has …

Introduction Chordomas are aggressive tumors that are thought to arise from remnants of the
embryological notochord. They can arise along the ventromedial aspect of the sacrum …