Disruption of the mouse dopamine transporter gene results in spontaneous hyperlocomotion
despite major adaptive changes, such as decreases in neurotransmitter and receptor levels …

Cocaine is believed to work by blocking the dopamine transporter (DAT) and thereby
increasing the availability of free dopamine within the brain1–4. Although this concept is …

The action of dopamine and other monoamine neurotransmitters at synapses is terminated
predominantly by high-affinity reuptake into presynaptic terminals by specific sodium …

The plasma membrane dopamine transporter (DAT) is responsible for clearing dopamine
from the synapse. Cocaine blockade of DAT leads to increased extracellular dopamine, an …

The dopamine transporter (DAT) plays an important role in calibrating the duration and
intensity of dopamine neurotransmission in the central nervous system. We have used a …

The dopamine system is implicated in the control of locomotion, cognition, and endocrine
function, The relative contribution of the various dopamine‐related components is not well …

The dopamine transporter mediates uptake of dopamine into neurons and is a major target
for various pharmacologically active drugs and environmental toxins. Since its cloning, much …

We have screened a human substantia nigra cDNA library with probes derived from the rat
dopamine transporter. A 3.5-kilobase cDNA clone was isolated and its corresponding gene …

A rat dopamine (DA) transporter complementary DNA has been isolated with combined
complementary DNA homology and expression approaches. The DA transporter is a 619 …

A human dopamine transporter cDNA was cloned and transfected into COS-7 cells, a cell
line that lacks vesicular storage and release mechanisms. Cells expressing the dopamine …