Optimal use of microbiology laboratories is essential to combat the spread of multiply
antibiotic-resistant pathogens. This is vital for patient care, as advocated by Jarvis in …

Many clinical laboratories have problems detecting extended-spectrum beta-lactamases
(ESBLs) and plasmid-mediated AmpC beta-lactamases. Confusion exists about the …

Extended-spectrum β-lactamases (ESBLs) are enzymes produced in some gram-negative
bacilli that mediate resistance to extended-spectrum cephalosporins and aztreonam. They …

Extended-spectrum β-lactamases (ESBLs) are plasmid-mediated bacterial enzymes that
confer resistance to a broad range of β-lactams. They are descended by genetic mutation …

Newer β-lactamases such as extended-spectrum β-lactamases (ESBLs), transferable AmpC
β-lactamases, and carbapenemases are associated with laboratory testing problems of false …

The production of β-lactamase is the principal mechanism by which gram-negative bacteria
resist the action of β-lactam antibiotics. In recent decades, there has been an alarming …

Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum
β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …

Objective: To review the laboratory diagnosis of extended-spectrum β-lactamase (ESBL)
and AmpC β-lactamase–producing bacteria and evaluate potential treatment options. Data …

Plasmids encoding extended-spectrum beta-lactamases of the TEM, SHV, and AmpC
families were introduced into common Escherichia coli and Klebsiella pneumoniae hosts to …