The role of circadian rhythms in Obstructive Sleep Apnea symptoms and novel targets for treatment
I Soreca - Chronobiology International, 2021 - Taylor & Francis
ABSTRACT Obstructive Sleep Apnea (OSA) is a common disorder that is associated with
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …
Is obstructive sleep apnea a circadian rhythm disorder?
J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …
Circadian dysregulation: the next frontier in obstructive sleep apnea research
DC von Allmen, LJ Francey… - … –Head and Neck …, 2018 - journals.sagepub.com
Objective To review the effects of the circadian clock on homeostasis, the functional
interaction between the circadian clock and hypoxia-inducible factors, and the role of …
interaction between the circadian clock and hypoxia-inducible factors, and the role of …
[HTML][HTML] Circadian biology in obstructive sleep apnea
BSC Koritala, Z Conroy, DF Smith - Diagnostics, 2021 - mdpi.com
Obstructive sleep apnea (OSA) is a complex process that can lead to the dysregulation of
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …
Circadian Rhythm Sleep-Wake Disorders
RR Auger - An Evidence-Based Guide for Clinicians and …, 2020 - Springer
Identification and treatment of circadian rhythm sleep-wake disorders (CRSWDs) can be a
fascinating yet vexing clinical encounter in the Sleep Medicine realm. While circadian-based …
fascinating yet vexing clinical encounter in the Sleep Medicine realm. While circadian-based …
[HTML][HTML] Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea
Abstract Background Obstructive Sleep Apnea (OSA) is a highly prevalent and
underdiagnosed sleep disorder. Recent studies suggest that OSA might disrupt the …
underdiagnosed sleep disorder. Recent studies suggest that OSA might disrupt the …
The circadian system contributes to apnea lengthening across the night in obstructive sleep apnea
MP Butler, C Smales, H Wu, MV Hussain, YA Mohamed… - Sleep, 2015 - academic.oup.com
Abstract Study Objective: To test the hypothesis that respiratory event duration exhibits an
endogenous circadian rhythm. Design: Within-subject and between-subjects. Settings …
endogenous circadian rhythm. Design: Within-subject and between-subjects. Settings …
[HTML][HTML] Basic chronobiology: what do sleep physicians need to know?
NFW Zaki, DW Spence, P Subramanian… - Sleep …, 2020 - thieme-connect.com
Sleep is an essential physiological process, which profoundly affects a wide range of
biological activities. It is now known that sleep supports myriad vital functions in the central …
biological activities. It is now known that sleep supports myriad vital functions in the central …
[HTML][HTML] Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene …
Intermittent hypoxia (IH) is a major clinical feature of obstructive sleep apnea (OSA). The
mechanisms that become dysregulated after periods of exposure to IH are unclear …
mechanisms that become dysregulated after periods of exposure to IH are unclear …
Do circadian rhythms in respiratory control contribute to sleep-related breathing disorders?
R Stephenson - Sleep medicine reviews, 2003 - Elsevier
Sleep-related respiratory dysfunction compromises the health and quality of life of millions of
people worldwide, underscoring the need for a full understanding of the mechanisms by …
people worldwide, underscoring the need for a full understanding of the mechanisms by …