Diabetic cardiomyopathy (DCM) is one serious and common complication in diabetes
without effective treatments. Hydrogen sulfide (H 2 S) fights against a variety of …

Background Previous studies have suggested that exogenous hydrogen sulfide can
alleviate the development of diabetic cardiomyopathy (DCM) by inhibiting oxidative stress …

Diabetic cardiomyopathy (DCM) is a significant contributor to the morbidity and mortality
associated with diabetes and metabolic syndrome. Retinoids, through activation of retinoic …

The nuclear receptor retinoic acid-related orphan receptor-α (RORα) regulates numerous
critical biological processes, including central nervous system development, lymphocyte …

Background Hyperglycemia-induced reactive oxygen species (ROS) generation contributes
to development of diabetic cardiomyopathy. Nuclear factor E2-related factor 2 (Nrf2), a redox …

The biological actions of retinoids are mediated by nuclear retinoic acid receptors (RARs)
and retinoid X receptors (RXRs). We have recently reported that decreased expression of …

Retinoid-related orphan receptor α (RORα), a member of the metabolic nuclear receptor
superfamily, plays a vital regulatory role in circadian rhythm and metabolism. Here, we …

Diabetic cardiomyopathy is a major complication that significantly contributes to morbidity
and mortality in diabetics with few therapies. Moreover, antidiabetic drugs reported …

Diabetes mellitus (DM) is a primary risk factor for cardiovascular diseases and heart failure.
Activation of the retinoic acid receptor (RAR) and retinoid X receptor (RXR) has an anti …

We have previously shown that retinoic acid (RA) has protective effects on high glucose
(HG)‐induced cardiomyocyte apoptosis. To further elucidate the molecular mechanisms of …