Besides its importance as a livestock species, pig is increasingly being used as an animal
model for biomedical research. Macrophages play critical roles in immunity to pathogens …

Considering that macrophage functions are strongly impacted by the local tissue
environment and the type of immune response, the aim of this study was to carefully set the …

Monocytes and macrophages belong to the mononuclear phagocyte system and play
important roles in both physiological and pathological processes. The cells belonging to the …

Macrophages are widely distributed in most tissues of the body, where they play important
roles in host defense and repair of tissue damage. In this report we describe the production …

Porcine monocyte-derived macrophages (moMΦ) have been employed as a model cell in
numerous studies of the porcine immune system. However, the lack of a standardized …

Background The draft genome of the domestic pig (Sus scrofa) has recently been published
permitting refined analysis of the transcriptome. Pig breeds have been reported to differ in …

In mammals, the immune system is undergoing significant changes during development,
which has many impacts on the individual's capacity to cope with infectious diseases or …

Macrophages are a heterogeneous population of cells that are present in all vertebrate
tissues. They play a key role in the innate immune system, and thus, in vitro cultures of …

Pigs are a major food source worldwide as well as major biomedical models for human
physiology and therapeutics. A thorough understanding of porcine immunity is essential to …

Peripheral blood monocytes of several species can be divided into different subpopulations
with distinct phenotypic and functional properties. Herein, we aim at reviewing published …