Macrophages are versatile immune cells and can adapt to both external stimuli and their
surrounding environment. Macrophages are categorized into two major categories; M1 …

The head and neck tumor microenvironment (TME) is highly infiltrated with macrophages.
More specifically, tumor-associated macrophages (TAM/M2-like) are one of the most critical …

Immunotherapy has made great progress in recent years, yet the efficacy of solid tumors
remains far less than expected. One of the main hurdles is to overcome the immune …

Tumor-associated macrophages (TAMs) contribute to breast cancer progression and
dissemination; TAM-targeting strategies aimed at their reprogramming show promising …

Anti-tumor M1-like and pro-tumor M2-like tumor-associated macrophages (TAMs) coexist in
tumor microenvironments (TME). The adverse effects of these M1/M2 subsets on tumors …

The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages
are historically regarded as anti-tumor, while M2-polarized macrophages, commonly …

The tumour microenvironment (TME) is composed of extracellular matrix and non-mutated
cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) …

Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

Different stimuli can polarize macrophages into two basic types, M1 and M2. Tumor-
associated macrophages (TAMs) in the tumor microenvironment (TME) are composed of …

Macrophages exhibit phenotypic heterogeneity under both physiological and pathological
conditions. Applications targeting M2-like tumor-associated macrophages (TAMs) improve …