One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that
occurs in response to resistance exercise. A large body of work shows that a mammalian …

Maintaining skeletal muscle mass and function is critical for disease prevention, mobility and
quality of life, and whole-body metabolism. Resistance exercise is known to be a major …

Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

For over 10 years, we have known that the activation of the mammalian target of rapamycin
complex 1 (mTORC1) has correlated with the increase in skeletal muscle size and strength …

Resistance training-induced muscle anabolism and subsequent hypertrophy occur most
rapidly during the early phase of training and become progressively slower over time …

Non‐technical summary Hypertrophy of skeletal muscle in response to resistance exercise
is associated with significantly elevated rates of protein synthesis. The protein kinase …

It is well known that an increase in mechanical loading can induce skeletal muscle
hypertrophy, and a long standing model in the field indicates that mechanical loads induce …

Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …

Resistance exercise (RE) activates signalling by the mammalian target of rapamycin
(mTOR) and it has been suggested that rapamycin-sensitive mTOR signalling controls RE …

Resistance exercise induces a hypertrophic response in skeletal muscle and recent studies
have begun to shed light on the molecular mechanisms involved in this process. For …