Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …

Focal adhesions (FAs) are specialized sites of cell attachment to the extracellular matrix
(ECM) where integrin receptors link the ECM to the actin cytoskeleton. Integrins cluster into …

Interactions of cells with the extracellular matrix are essential for the control of tissue
remodelling, cell migration, and embryogenesis. At the cell–extracellular matrix contact …

Focal adhesions (FAs) are macromolecular complexes that regulate cell adhesion and
mechanotransduction. By performing fluorescence recovery after photobleaching (FRAP) …

In focal adhesions of eukaryotic cells, transmembrane receptors of the integrin family and a
large set of adaptor proteins form the physical link between the extracellular substrate and …

Focal adhesions (FAs) are multiprotein structures that link the intracellular cytoskeleton to
the extracellular matrix. They mediate cell adhesion and migration, crucial to many (patho-) …

Focal adhesions (FAs) are mechanosensitive adhesion and signaling complexes that grow
and change composition in response to myosin II–mediated cytoskeletal tension in a …

Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin
cytoskeleton. Cells modify focal adhesions in response to changes in the molecular …

Focal adhesions have been intensely studied ever since their discovery in 1971. The last
three decades have seen major advances in understanding the structure of focal adhesions …

Focal adhesions (FAs) are macromolecular complexes that provide a linkage between the
cell and its external environment. In a motile cell, focal adhesions change size and position …