Evolution of genome-organizing long non-coding RNAs in metazoans
A Ramírez-Colmenero, K Oktaba… - Frontiers in …, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) have important regulatory functions across eukarya. It is
now clear that many of these functions are related to gene expression regulation through …
now clear that many of these functions are related to gene expression regulation through …
Long noncoding RNAs in organogenesis: making the difference
P Grote, BG Herrmann - Trends in Genetics, 2015 - cell.com
A large proportion of the cellular transcriptome of higher vertebrates consists of non-protein
coding transcripts, among them the long noncoding RNAs (lncRNAs). Although lncRNAs are …
coding transcripts, among them the long noncoding RNAs (lncRNAs). Although lncRNAs are …
lncRNAs: linking RNA to chromatin
JL Rinn - Cold Spring Harbor perspectives in biology, 2014 - cshperspectives.cshlp.org
Numerous studies over the past decade have identified increasing numbers of long
noncoding RNAs (lncRNAs) across many organisms. Research since has shown that …
noncoding RNAs (lncRNAs) across many organisms. Research since has shown that …
Long noncoding RNAs: an emerging link between gene regulation and nuclear organization
S Quinodoz, M Guttman - Trends in cell biology, 2014 - cell.com
Mammalian genomes encode thousands of long noncoding RNAs (lncRNAs) that play
important roles in diverse biological processes. As a class, lncRNAs are generally enriched …
important roles in diverse biological processes. As a class, lncRNAs are generally enriched …
Chromatin and RNA maps reveal regulatory long noncoding RNAs in mouse
Discovering and classifying long noncoding RNAs (lncRNAs) across all mammalian tissues
and cell lines remains a major challenge. Previously, mouse lncRNAs were identified using …
and cell lines remains a major challenge. Previously, mouse lncRNAs were identified using …
The role of long non-coding RNAs in chromatin structure and gene regulation: variations on a theme
D Umlauf, P Fraser, T Nagano - 2008 - degruyter.com
Transcriptome studies have uncovered a plethora of non-coding RNAs (ncRNA) in
mammals. Most originate within intergenic regions of the genome and recent evidence …
mammals. Most originate within intergenic regions of the genome and recent evidence …
Evolution to the rescue: using comparative genomics to understand long non-coding RNAs
I Ulitsky - Nature Reviews Genetics, 2016 - nature.com
Long non-coding RNAs (lncRNAs) have emerged in recent years as major players in a
multitude of pathways across species, but it remains challenging to understand which of …
multitude of pathways across species, but it remains challenging to understand which of …
lncRNAs in development and differentiation: from sequence motifs to functional characterization
F Constanty, A Shkumatava - Development, 2021 - journals.biologists.com
The number of long noncoding RNAs (lncRNAs) with characterized developmental and
cellular functions continues to increase, but our understanding of the molecular mechanisms …
cellular functions continues to increase, but our understanding of the molecular mechanisms …
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs
Background Recent advances in transcriptome sequencing have enabled the discovery of
thousands of long non-coding RNAs (lncRNAs) across many species. Though several …
thousands of long non-coding RNAs (lncRNAs) across many species. Though several …
LncRNAs in vertebrates: advances and challenges
AC Mallory, A Shkumatava - Biochimie, 2015 - Elsevier
Beyond the handful of classic and well-characterized long noncoding RNAs (lncRNAs),
more recently, hundreds of thousands of lncRNAs have been identified in multiple species …
more recently, hundreds of thousands of lncRNAs have been identified in multiple species …