Environmental dimensions of the protein corona

KE Wheeler, AJ Chetwynd, KM Fahy, BS Hong… - Nature …, 2021 - nature.com
The adsorption of biomolecules to the surface of engineered nanomaterials, known as
corona formation, defines their biological identity by altering their surface properties and …

[HTML][HTML] The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Nanoparticle-protein corona complex: understanding multiple interactions between environmental factors, corona formation, and biological activity

A Tomak, S Cesmeli, BD Hanoglu, D Winkler… - …, 2021 - Taylor & Francis
The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids,
forming the so-called protein corona. The corona modifies key physicochemical …

Protein corona: opportunities and challenges

S Zanganeh, R Spitler, M Erfanzadeh… - The international journal …, 2016 - Elsevier
In contact with biological fluids diverse type of biomolecules (eg, proteins) adsorb onto
nanoparticles forming protein corona. Surface properties of the coated nanoparticles, in …

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

CD Walkey, WCW Chan - Chemical Society Reviews, 2012 - pubs.rsc.org
Nanomaterials hold promise as multifunctional diagnostic and therapeutic agents. However,
the effective application of nanomaterials is hampered by limited understanding and control …

[HTML][HTML] Impact of protein corona on the biological identity of nanomedicine: understanding the fate of nanomaterials in the biological milieu

MH Akhter, H Khalilullah, M Gupta, MA Alfaleh… - Biomedicines, 2021 - mdpi.com
Nanoparticles (NPs) in contact with a biological medium are rapidly comprehended by a
number of protein molecules resulting in the formation of an NP–protein complex called …

Chemical and biophysical signatures of the protein corona in nanomedicine

J Ren, N Andrikopoulos, K Velonia… - Journal of the …, 2022 - ACS Publications
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …

Exploiting the novel properties of protein coronas: emerging applications in nanomedicine

K Hamad-Schifferli - Nanomedicine, 2015 - Taylor & Francis
Protein coronas have been the focus of a great deal of study recently due to their inevitable
formation and their impact on the biological consequences of nanomaterials. Although the …

The crown and the scepter: roles of the protein corona in nanomedicine

R Cai, C Chen - Advanced Materials, 2019 - Wiley Online Library
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …

No king without a crown–impact of the nanomaterial-protein corona on nanobiomedicine

D Docter, S Strieth, D Westmeier, O Hayden… - …, 2015 - Taylor & Francis
Besides the wide use of nanomaterials in technical products, their application spectrum in
biotechnology and biomedicine is steadily increasing. Whereas the physico-chemical …