Copper radionuclides and radiopharmaceuticals in nuclear medicine

PJ Blower, JS Lewis, J Zweit - Nuclear medicine and biology, 1996 - Elsevier
The chemistry, radiochemistry, radiobiology, and radiopharmacology of
radiopharmaceuticals containing copper radionuclides are reviewed. Copper radionuclides …

Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals

Z Cai, CJ Anderson - Journal of labelled compounds and …, 2014 - Wiley Online Library
The development of chelating agents for copper radionuclides in positron emission
tomography radiopharmaceuticals has been a highly active and important area of study in …

Copper chelation chemistry and its role in copper radiopharmaceuticals

TJ Wadas, EH Wong, GR Weisman… - Current …, 2007 - ingentaconnect.com
Molecular imaging is an important scientific discipline that plays a major role in clinical
medicine and pharmaceutical development. While several imaging modalities including X …

64Cu-based Radiopharmaceuticals in Molecular Imaging

Y Zhou, J Li, X Xu, M Zhao, B Zhang… - … in cancer research & …, 2019 - journals.sagepub.com
Copper-64 (T1/2= 12.7 hours; β+: 19%, β−: 38%) has a unique decay profile and can be
used for positron emission tomography imaging and radionuclide therapy. The well …

Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals

PS Donnelly - Dalton Transactions, 2011 - pubs.rsc.org
There are several isotopes of copper and rhenium that are of interest in the development of
new molecular imaging or radiotherapeutic agents. This perspective article highlights the …

The emerging role of copper-64 radiopharmaceuticals as cancer theranostics

A Boschi, P Martini, E Janevik-Ivanovska, A Duatti - Drug Discovery Today, 2018 - Elsevier
Highlights•Copper radionuclides for in vivo imaging of biological functions of copper
ions.•Copper-64 has suitable nuclear properties for cancer theranostics.•Radioactive copper …

Copper radiopharmaceuticals for theranostic applications

A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …

Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research

CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …