Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

Ischemic stroke triggers a complex and highly interconnected cascade of cellular and
molecular events. Early events induced following ischemic injury, including excitotoxicity …

There is an urgent need for improved diagnostics and therapeutics for acute ischemic stroke.
This is the focus of numerous research projects involving in vitro studies, animal models and …

Stroke continues to be a major cause of death and disability. The currently available
therapies have proven to be highly unsatisfactory (except thrombolysis) and attempts are …

Stroke is the leading cause of disabilities and cognitive deficits, accounting for 5.2% of all
mortalities worldwide. Transient or permanent occlusion of cerebral vessels leads to …

The management of acute ischemic stroke has not made significant strides since the
introduction of recombinant tissue plasminogen activator (r-TPA) two decades ago. The use …

Background—Vascular damage caused by cerebral ischemia leads to edema, hemorrhage
formation, and worsened outcomes in ischemic stroke patients. Therapeutic interventions …

Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Stroke is the second most common cause of global death following coronary artery disease.
Time is crucial in managing stroke to reduce the rapidly progressing insult of the ischemic …

Acute ischemic stroke is a critical condition that can result in disability and death. The
consequences of this medical condition depend on various factors, including the size of the …