Oxysterols, the oxidized forms of cholesterol or of its precursors, are formed in the first steps
of cholesterol metabolism. Oxysterols have interested chemists, biologists, and physicians …

Intermediates of both cholesterol synthesis and cholesterol metabolism can have diverse
roles in the control of cellular processes that go beyond the control of cholesterol …

Cholesterol has typically been considered an exogenous, disease-related factor in
immunity; however, recent literature suggests that a paradigm shift is in order. Sterols are …

Cholesterol and its oxidized forms, oxysterols, are ingested from foods and are synthesized
de novo. Cholesterol and oxysterols influence molecular and cellular events and …

Editorial: 25-Hydroxycholesterol: a new life in immunology - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Cholesterol is an essential structural component of all membranes of mammalian cells
where it plays a fundamental role not only in cellular architecture, but also, for example, in …

Intermediates in the cholesterol-biosynthetic pathway and oxysterol derivatives of
cholesterol regulate diverse cellular processes. Recent studies have expanded the …

Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …

Oxysterols are cholesterol metabolites now considered bona fide bioactive lipids. Recent
studies have identified new receptors for oxysterols involved in immune and inflammatory …

Oxysterols, or cholesterol oxidation products, are naturally occurring lipids which regulate
the physiology of cells, including those of the immune system. In contrast to effects that are …