Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

AM Jastorff, K Haegler, G Maccarrone… - PROTEOMICS …, 2009 - Wiley Online Library
Multiple sclerosis is characterized by inflammatory demyelination and axonal loss as
pathophysiological correlates of relapsing activity and progressive development of clinical …

Identification of protein networks involved in the disease course of experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

A Vanheel, R Daniels, S Plaisance, K Baeten… - PLoS …, 2012 - journals.plos.org
A more detailed insight into disease mechanisms of multiple sclerosis (MS) is crucial for the
development of new and more effective therapies. MS is a chronic inflammatory autoimmune …

Proteome analysis of brain in murine experimental autoimmune encephalomyelitis

AS Fazeli, D Nasrabadi, MH Sanati, A Pouya… - …, 2010 - Wiley Online Library
Multiple sclerosis is considered a prototype inflammatory autoimmune disorder of the CNS.
Experimental autoimmune encephalomyelitis (EAE) induced by myelin oligodendrocyte …

Profiling and identification of cerebrospinal fluid proteins in a rat EAE model of multiple sclerosis

T Rosenling, MP Stoop, A Attali, H Aken… - Journal of proteome …, 2012 - ACS Publications
The experimental autoimmune encephalomyelitis (EAE) model resembles certain aspects of
multiple sclerosis (MScl), with common features such as motor dysfunction, axonal …

The experimental autoimmune encephalomyelitis model for proteomic biomarker studies: from rat to human

T Rosenling, A Attali, TM Luider, R Bischoff - Clinica chimica acta, 2011 - Elsevier
Multiple sclerosis (MScl) is defined by central nervous system (CNS) inflammation,
demyelination and axonal damage. Some of the disease mechanisms are known but the …

Proteome analysis of spinal cord during the clinical course of monophasic experimental autoimmune encephalomyelitis

AS Farias, D Martins‐de‐Souza, L Guimaraes… - …, 2012 - Wiley Online Library
The induction of autoimmune encephalomyelitis (EAE) in L ewis rats results in a period of
exacerbation followed by complete recovery. Therefore, this model is widely used for …

Proteomic strategies in multiple sclerosis and its animal models

S Elkabes, H Li - PROTEOMICS–Clinical Applications, 2007 - Wiley Online Library
The early and precise diagnosis, the prognosis, and the clinical management of multiple
sclerosis, remain a considerable challenge. In recent years, the development of novel and …

Toward a combination of biomarkers for molecular characterization of multiple sclerosis

D Birmpili, I Charmarke Askar, LD Pham-Van… - International Journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
associated with chronic inflammation, demyelination, and axonal damage. MS is a highly …

Proteome profiling in murine models of multiple sclerosis: identification of stage specific markers and culprits for tissue damage

RA Linker, P Brechlin, S Jesse, P Steinacker, DH Lee… - PloS one, 2009 - journals.plos.org
The identification of new biomarkers is of high interest for the prediction of the disease
course and also for the identification of pathomechanisms in multiple sclerosis (MS). To …

Quantitative Proteome Profiling of CNS-Infiltrating Autoreactive CD4+ Cells Reveals Selective Changes during Experimental Autoimmune Encephalomyelitis

ME Turvey, T Koudelka, I Comerford… - Journal of Proteome …, 2014 - ACS Publications
Experimental autoimmune encephalomyelitis (EAE) is a murine model of multiple sclerosis,
a chronic neurodegenerative and inflammatory autoimmune condition of the central nervous …